Evidence map›Paper›PMID 29318371›Full record

ReviewHerzschrittmachertherapie & Elektrophysiologie2018

Proteomics and transcriptomics in atrial fibrillation.

Marc Sühling, Carmen Wolke, Christian Scharf, Uwe Lendeckel

Abstract readReview
PubMed Publisher
In one paragraph

Review in Herzschrittmachertherapie & Elektrophysiologie, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Effect of Occurrence of Lamin A/C (Frontiers in cardiovascular medicine · 2022
    Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marc SühlingInstitute of Medical Biochemistry and Molecular Biology, University Medicine Greifswald, Ernst Moritz Arndt University Greifswald, Ferdinand-Sauerbruch-Straße, 17475, Greifswald, Germany.
Carmen WolkeInstitute of Medical Biochemistry and Molecular Biology, University Medicine Greifswald, Ernst Moritz Arndt University Greifswald, Ferdinand-Sauerbruch-Straße, 17475, Greifswald, Germany.
Christian ScharfDepartment of Otorhinolaryngology, Head and Neck Surgery, University Medicine Greifswald, Ernst Moritz Arndt University Greifswald, Greifswald, Germany.
Uwe LendeckelInstitute of Medical Biochemistry and Molecular Biology, University Medicine Greifswald, Ernst Moritz Arndt University Greifswald, Ferdinand-Sauerbruch-Straße, 17475, Greifswald, Germany. uwe.lendeckel@uni-greifswald.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atrial fibrillation (AF) is the most common tachyarrhythmia. AF, due to substantial remodeling processes initiated in the atria, is a typically self-sustaining and progressive disease. Atrial remodeling has been intensively investigated at the molecular level in recent decades. Although the application of "omics" technologies has already significantly contributed to our current understanding of the pathophysiology of AF, the complexity of the latter and the large heterogeneity of AF patients remained a major limitation. With the advent of novel "omics" and by applying integrative approaches, it will be possible to extract more information and push boundaries. The present review will summarize the contribution of transcriptomics and proteomics to our understanding of the pathophysiology of AF.

Indexed as

ProteomicsAtrial FibrillationAtrial RemodelingHeart AtriaHumansPhosphorylationProtein Array AnalysisSequence Analysis, RNATranscriptomeTwo-Dimensional Difference Gel Electrophoresis2D-DIGEMicroarray technologyRapid-pacingRNA sequencingTranscriptome

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.