Observational studyDiabetologia2018
Short-term progression of cardiometabolic risk factors in relation to age at type 2 diabetes diagnosis: a longitudinal observational study of 100,606 individuals from the Swedish National Diabetes Register.
Observational study in Diabetologia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT04688359 (Nurse-coordinated Follow-up Program in Primary Care), which is not on this map. Cited by 44 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Nurse-coordinated Follow-up Program in Primary Care: a Mixed-method Complex Intervention Feasibility and RCT Pilot Trial Among People at Risk for T2DM.
Who cites it
44 citing papers in PubMed, 3 syntheses or guidelines pooled it, 87 citations in OpenAlex.
- Comprehensive Factors for Predicting the Complications of DiabetesMellitus: A Systematic Review.Current diabetes reviews · 2024Pooled it
- Age dependent associations of risk factors with heart failure: pooled population based cohort study.BMJ (Clinical research ed.) · 2021Pooled it
- Aspects of Multicomponent Integrated Care Promote Sustained Improvement in Surrogate Clinical Outcomes: A Systematic Review and Meta-analysis.Diabetes care · 2018Pooled it
- Using HbA1c measurements and the Finnish Diabetes Risk Score to identify undiagnosed individuals and those at risk of diabetes in primary care.BMC public health · 2023Trial
- Age-related patterns of cardiometabolic risk factors for complications in type 2 diabetes.Diabetologia · 2026Article
- A call to action: A consensus statement on knowledge gaps and research priorities on the management of women with early onset type 2 diabetes in the preconception, pregnancy and postnatal periods: A report from the Diabetic Medicine Symposium at the Diabetes UK Annual Professional Conference, 2025.Diabetic medicine : a journal of the British Diabetic Association · 2026Article
- Diabetic Cardiovascular Complications in Women and Young Adults.Current epidemiology reports · 2026Review
- Metabolic syndrome and the risk of incident heart failure: a prospective cohort study.American journal of preventive cardiology · 2025Article
- Association of oxidative balance score with the risk of all-cause and CVD mortality in younger US adults with diabetes.Scientific reports · 2025Article
- Association between age at diagnosis of diabetes and ocular disease: Insights from a recent article.World journal of diabetes · 2025Article
- Metabolic syndrome, high-sensitivity C-reactive protein and the risk of heart failure: the Kailuan cohort study.Frontiers in endocrinology · 2025Article
- Steatotic Liver Disease in Pediatric Obesity and Increased Risk for Youth-Onset Type 2 Diabetes.Diabetes care · 2024Article
- Article
- Obesity increases the risk of hepatic fibrosis in young adults with type 2 diabetes mellitus: the need to screen.Obesity (Silver Spring, Md.) · 2024Article
- Association between age at diagnosis and all-cause mortality in type 2 diabetes: the Renal Insufficiency and Cardiovascular Events (RIACE) Italian Multicenter Study.Acta diabetologica · 2024Observational
- Association of age at diagnosis of diabetes with subsequent risk of age-related ocular diseases and vision acuity.World journal of diabetes · 2024Article
- Association Between Age at Diagnosis of Type 2 Diabetes and Hospitalization for Heart Failure: A Population-Based Study.Journal of the American Heart Association · 2024Article
- High prevalence of retinopathy in young-onset type 2 diabetes and possible sex differences: insights from Norwegian general practice.BMJ open diabetes research & care · 2024Article
- Age at diagnosis of diabetes, obesity, and the risk of dementia among adult patients with type 2 diabetes.PloS one · 2024Article
- Life expectancy associated with different ages at diagnosis of type 2 diabetes in high-income countries: 23 million person-years of observation.The lancet. Diabetes & endocrinology · 2023Observational
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aims/hypothesisThe reasons underlying a greater association of premature mortality with early-onset type 2 diabetes relative to late-onset disease are unclear. We evaluated the clinical characteristics at type 2 diabetes diagnosis and the broad trajectories in cardiometabolic risk factors over the initial years following diagnosis in relation to age at diagnosis.
methodsOur cohort consisted of 100,606 individuals with newly diagnosed type 2 diabetes enrolled in the Swedish National Diabetes Register from 2002 to 2012. The average follow-up time was 2.8 years. Analyses were performed using a linear mixed-effects model for continuous risk factors and a mixed generalised linear model with a logistic link function for dichotomous risk factors.
resultsThe individuals diagnosed at the youngest age (18-44 years) were more often male and had the highest BMI (mean of 33.4 kg/m CONCLUSIONS/
interpretationIndividuals who develop type 2 diabetes at a younger age are more frequently obese, display a more adverse lipid profile, have higher HbA
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