Evidence map›Paper›PMID 29318012›Full record

ReviewSAGE open medicine2017

Understanding and treating solid tumor-related disseminated intravascular coagulation in the "era" of targeted cancer therapies.

Felice Vito Vitale, Giuseppe Sa Longo-Sorbello, Stefano Rotondo, Francesco Ferrau

Open access · goldAbstract readReview
In one paragraph

Review in SAGE open medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact, top 78% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Felice Vito VitaleDivisione di Oncologia Medica, Ospedale San Vincenzo, Messina, Italy.
Giuseppe Sa Longo-SorbelloDivisione di Ematologia, Ospedale San Vincenzo, Messina, Italy.
Stefano RotondoAmbulatorio Diagnostica Vascolare, Angiologia e Medicina Interna, IRCCS Piemonte-Bonino Pulejo, Messina, Italy.
Francesco FerrauDivisione di Oncologia Medica, Ospedale San Vincenzo, Messina, Italy.
Medica (Italy) · ITCentro Neurolesi Bonino Pulejo · ITFondazione Vincenzo Pansadoro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A systemic activation of blood coagulation is usually present in many clinical conditions including the infectious or inflammatory ones and malignant disease as well. Depending upon circumstances, patients suffering from acute decompensated disseminated intravascular coagulation may be managed by a medical oncologist and either an internist or a physician working in an emergency and/or intensive care unit. In some cases, for example, the indolent ones, the activation of coagulation might not be easily detected by routine laboratory tests and not lead to clinical manifestations. Such a chronically activated intravascular coagulation can progress toward an overt decompensated disseminated intravascular coagulation. Traditional therapy of decompensated disseminated intravascular coagulation is based on reversing the underlying triggering disease and providing patients with adequate supportive treatment. The dilemma for the oncologist is whether or not the trigger cause can be treated and amended with a specific antineoplastic treatment, without worsening the consumption of platelets and the risk of bleeding. In light of the availability of new targeted therapies, the main criteria that should drive the strategy against solid cancer-related disseminated intravascular coagulation will be discussed.

Indexed as

Cancerdisseminated intravascular coagulationsolid tumors

Identifiers

PMID29318012
PMCPMC5753895
OpenAlexW2779438497

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.