ArticleOncoTargets and therapy2018
Four-miRNA signature as a prognostic tool for lung adenocarcinoma.
Article in OncoTargets and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Systemic analysis of 1,4-dichlorobenzenes effects on lung adenocarcinoma environmental exposure and core target regulation prediction.Discover oncology · 2026Article
- Mir-421 and mir-550a-1 are potential prognostic markers in esophageal adenocarcinoma.Biology direct · 2023Article
- Identification of a 7-miRNA signature for predicting the prognosis of patients with lung adenocarcinoma.Experimental biology and medicine (Maywood, N.J.) · 2022Article
- miR-31-5p modulates cell progression in lung adenocarcinoma through TNS1/p53 axis.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2022Article
- Transcriptome Analysis of Ivosidenib-Mediated Inhibitory Functions on Non-Small Cell Lung Cancer.Frontiers in oncology · 2021Article
- Essential Genes and MiRNA-mRNA Network Contributing to the Pathogenesis of Idiopathic Pulmonary Arterial Hypertension.Frontiers in cardiovascular medicine · 2021Article
- Risk Score Based on Two microRNAs as a Prognostic Marker of Hepatocellular Carcinoma and the Corresponding Competitive Endogenous RNA Network.International journal of general medicine · 2021Article
- Non-Coding RNAs as Prognostic Biomarkers: A miRNA Signature Specific for Aggressive Early-Stage Lung Adenocarcinomas.Non-coding RNA · 2020Article
- A seven-miRNA expression-based prognostic signature and its corresponding potential competing endogenous RNA network in early pancreatic cancer.Experimental and therapeutic medicine · 2019Article
- Clinical value of microRNA-198-5p downregulation in lung adenocarcinoma and its potential pathways.Oncology letters · 2019Article
- Identification of key genes involved in the metastasis of clear cell renal cell carcinoma.Oncology letters · 2019Article
- Article
- Construction and validation of a seven-microRNA signature as a prognostic tool for lung squamous cell carcinoma.Cancer management and research · 2019Article
- TBX21 predicts prognosis of patients and drives cancer stem cell maintenance via the TBX21-IL-4 pathway in lung adenocarcinoma.Stem cell research & therapy · 2018Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to generate a novel miRNA expression signature to accurately predict prognosis for patients with lung adenocarcinoma (LUAD). PATIENTS AND
methodsUsing expression profiles downloaded from The Cancer Genome Atlas database, we identified multiple miRNAs with differential expression between LUAD and paired healthy tissues. We then evaluated the prognostic values of the differentially expressed miRNAs using univariate/multivariate Cox regression analysis. This analysis was ultimately used to construct a four-miRNA signature that effectively predicted patient survival. Finally, we analyzed potential functional roles of the target genes for these four miRNAs using Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses.
resultsBased on our cutoff criteria (
conclusionTaken together, our results suggest that our four-miRNA signature can be used as a prognostic tool for patients with LUAD.
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