Evidence map›Paper›PMID 29317798›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2018

Visual outcomes, efficacy, and surgical complications associated with intracameral phenylephrine 1.0%/ketorolac 0.3% administered during cataract surgery.

Eric D Rosenberg, Alanna S Nattis, David Alevi, Rachel L Chu, Joseph Bacotti, Ronald J LoPinto, Gerald D'Aversa, Eric D Donnenfeld

Open access · goldAbstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Eric D RosenbergNew York Medical College, Valhalla, NY.
Alanna S NattisLindenhurst Eye Physicians and Surgeons, Babylon, NY.
David AleviOphthalmic Consultants of Long Island, Rockville Centre, NY.
Rachel L ChuCornell University, Ithaca, NY.
Joseph BacottiOphthalmic Consultants of Long Island, Rockville Centre, NY.
Ronald J LoPintoOphthalmic Consultants of Long Island, Rockville Centre, NY.
Gerald D'AversaOphthalmic Consultants of Long Island, Rockville Centre, NY.
Eric D DonnenfeldNew York University Medical Center, New York, NY, USA.
Ophthalmic Consultants of Long Island · USColumbia University Irving Medical Center · USCornell University · USNew York Medical College · USNorthwest Eye Surgeons · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe purpose of this study was to compare visual outcomes, surgical time, and perioperative surgical complications after intracameral use of either phenylephrine/ketorolac (P/K) or epinephrine (Epi) during cataract surgery.

methodsThis was a single-center, retrospective case review of patients undergoing cataract surgery from August to November 2015. Of the 641 eyes of 389 patients who underwent cataract surgery, 260 eyes were administered phenylephrine 1.0%/ketorolac 0.3% and 381 eyes received Epi in the irrigation solution intraoperatively. All patients received a topical nonsteroidal anti-inflammatory drug regimen (bromfenac 0.07%, nepafenac 0.3%, or ketorolac 0.5%) for 3 days before surgery and topical tropicamide 1.0%, cyclopentolate 1.0%, and phenylephrine 2.5% on the day of surgery.

resultsMean length of surgery (LOS) was 15.4±0.6 minutes. Although a positive correlation was noted between patient age and LOS (

conclusionIntracameral use of phenylephrine 1.0%/ketorolac 0.3% during cataract surgery may be effective in maintaining mydriasis. It appears to be superior to intracameral Epi at reducing intraoperative and postoperative complications, need for pupillary dilating devices, and surgical time.

Indexed as

cataract surgerycomplicationsketorolacphenylephrinepupillary miosis

Identifiers

PMID29317798
PMCPMC5743109
OpenAlexW2779129795

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.