Evidence map›Paper›PMID 29317746›Full record

ArticleScientific reports2018

Refractive error is associated with intracranial volume.

Hikaru Takeuchi, Yasuyuki Taki, Rui Nouchi, Ryoichi Yokoyama, Yuka Kotozaki, Seishu Nakagawa, Atsushi Sekiguchi, Kunio Iizuka, Yuki Yamamoto, Sugiko Hanawa and 10 more

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Myopia in Beagles in a Family of 12 Individuals.Animals : an open access journal from MDPI · 2025
    Article
  2. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Hikaru TakeuchiDivision of Developmental Cognitive Neuroscience, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan. takehi@idac.tohoku.ac.jp.
Yasuyuki TakiDivision of Developmental Cognitive Neuroscience, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Rui NouchiCreative Interdisciplinary Research Division, Frontier Research Institute for Interdisciplinary Science, Tohoku University, Sendai, Japan.
Ryoichi YokoyamaSchool of Medicine, Kobe University, Kobe, Japan.
Yuka KotozakiDivision of Clinical research, Medical-Industry Translational Research Center, Fukushima Medical University School of Medicine, Fukushima, Japan.
Seishu NakagawaDepartment of Functional Brain Science, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Atsushi SekiguchiDivision of Medical Neuroimaging Analysis, Department of Community Medical Supports, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.
Kunio IizukaDepartment of Psychiatry, Tohoku University Graduate School of Medicine, Sendai, Japan.
Yuki YamamotoDepartment of Functional Brain Science, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Sugiko HanawaDepartment of Functional Brain Science, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Tsuyoshi ArakiSmart Ageing International Research Center, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Carlos Makoto MiyauchiGraduate School of Arts and Sciences, Department of General Systems Studies, The University of Tokyo, Tokyo, Japan.
Takamitsu ShinadaDepartment of Functional Brain Science, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Kohei SakakiDepartment of Functional Brain Science, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Yuko SassaDivision of Developmental Cognitive Neuroscience, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Takayuki NozawaDepartment of Ubiquitous Sensing, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.ORCID http://orcid.org/0000-0001-6300-4373
Shigeyuki IkedaDepartment of Ubiquitous Sensing, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Susumu YokotaDivision of Developmental Cognitive Neuroscience, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Magistro DanieleNational Centre for Sport and Exercise Medicine (NCSEM), The NIHR Leicester-Loughborough Diet, Lifestyle and Physical Activity Biomedical Research Unit, School of Sport, Exercise, and Health Sciences, Loughborough University, Loughborough, England.ORCID http://orcid.org/0000-0002-2554-3701
Ryuta KawashimaDivision of Developmental Cognitive Neuroscience, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myopia is part of the spectrum of refractive error. Myopia is associated with psychometric intelligence and, the link between brain anatomy and myopia has been hypothesized. Here we aimed to identify the associations between brain structures and refractive error in developed young adults. In a study cohort of 1,319 normal educated young adults, the refractive error showed a significant negative correlation with total intracranial volume and total cerebrospinal fluid (CSF) volume but not with total gray matter volume (GMV) or total white matter volume (WMV). Time spent studying was associated with refractive error but could not explain the aforementioned associations with brain volume parameters. The R

Indexed as

AdolescentAdultBrainFemaleHumansIntelligenceMagnetic Resonance ImagingMaleOrgan SizeRefractive Errors

Identifiers

PMID29317746
PMCPMC5760524

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.