Evidence map›Paper›PMID 29317683›Full record

ArticleScientific reports2018

Polyaniline cryogels: Biocompatibility of novel conducting macroporous material.

Petr Humpolíček, Katarzyna Anna Radaszkiewicz, Zdenka Capáková, Jiří Pacherník, Patrycja Bober, Věra Kašpárková, Petra Rejmontová, Marián Lehocký, Petr Ponížil, Jaroslav Stejskal

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 73 citations in OpenAlex.

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  7. Method forHeliyon · 2024
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  14. Electroactive Smart Polymers for Biomedical Applications.Materials (Basel, Switzerland) · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Petr HumpolíčekCentre of Polymer Systems, Tomas Bata University in Zlin, 760 01, Zlin, Czech Republic. humpolicek@utb.cz.ORCID http://orcid.org/0000-0002-6837-6878
Katarzyna Anna RadaszkiewiczInstitute of Experimental Biology, Faculty of Science, Masaryk University, 625 00, Brno, Czech Republic.
Zdenka CapákováCentre of Polymer Systems, Tomas Bata University in Zlin, 760 01, Zlin, Czech Republic.
Jiří PacherníkInstitute of Experimental Biology, Faculty of Science, Masaryk University, 625 00, Brno, Czech Republic.
Patrycja BoberInstitute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, 162 06, Prague 6, Czech Republic.
Věra KašpárkováCentre of Polymer Systems, Tomas Bata University in Zlin, 760 01, Zlin, Czech Republic.
Petra RejmontováCentre of Polymer Systems, Tomas Bata University in Zlin, 760 01, Zlin, Czech Republic.
Marián LehockýCentre of Polymer Systems, Tomas Bata University in Zlin, 760 01, Zlin, Czech Republic.
Petr PonížilCentre of Polymer Systems, Tomas Bata University in Zlin, 760 01, Zlin, Czech Republic.
Jaroslav StejskalInstitute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, 162 06, Prague 6, Czech Republic.
Tomas Bata University in Zlín · CZCzech Academy of Sciences, Institute of Macromolecular Chemistry · CZMasaryk University · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyaniline cryogel is a new unique form of polyaniline combining intrinsic electrical conductivity and the material properties of hydrogels. It is prepared by the polymerization of aniline in frozen poly(vinyl alcohol) solutions. The biocompatibility of macroporous polyaniline cryogel was demonstrated by testing its cytotoxicity on mouse embryonic fibroblasts and via the test of embryotoxicity based on the formation of beating foci within spontaneous differentiating embryonic stem cells. Good biocompatibility was related to low contents of low-molecular-weight impurities in polyaniline cryogel, which was confirmed by liquid chromatography. The adhesion and growth of embryonic stem cells, embryoid bodies, cardiomyocytes, and neural progenitors prove that polyaniline cryogel has the potential to be used as a carrier for cells in tissue engineering or bio-sensing. The surface energy as well as the elasticity and porosity of cryogel mimic tissue properties. Polyaniline cryogel can therefore be applied in bio-sensing or regenerative medicine in general, and mainly in the tissue engineering of electrically excitable tissues.

Indexed as

AlgorithmsAniline CompoundsAnimalsBiocompatible MaterialsCell Culture TechniquesCell SurvivalChromatography, High Pressure LiquidCryogelsElastic ModulusElectric ConductivityFibroblastsMaterials TestingMechanical PhenomenaMiceModels, TheoreticalPorosityAniline CompoundsBiocompatible MaterialsCryogelspolyaniline

Identifiers

PMID29317683
PMCPMC5760658
OpenAlexW2781901074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.