Evidence map›Paper›PMID 29317643›Full record

ArticleScientific reports2018

Multiple mutations and overexpression of the MdaE7 carboxylesterase gene associated with male-linked malathion resistance in housefly, Musca domestica (Diptera: Muscidae).

Yi Zhang, Jing Li, Zhuo Ma, Chao Shan, Xiwu Gao

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
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  5. Dichlorvos Resistance in the House Fly Populations,Journal of arthropod-borne diseases · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yi ZhangDepartment of Entomology, China Agricultural University, Beijing, 100193, P.R. China.
Jing LiBeijing Center for Diseases Prevention and Control, Beijing, 100013, China.
Zhuo MaDepartment of Entomology, China Agricultural University, Beijing, 100193, P.R. China.
Chao ShanDepartment of Entomology, China Agricultural University, Beijing, 100193, P.R. China.
Xiwu GaoDepartment of Entomology, China Agricultural University, Beijing, 100193, P.R. China. gaoxiwu@263.net.cn.
China Agricultural University · CNBeijing Center for Disease Prevention and Control · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two unique housefly strains, MSS and N-MRS, were selected and used to clarify mechanisms of sex-associated malathion resistance in the housefly, Musca domestica. Compared with the lab-susceptible CSS strain, susceptible females and resistant males were observed in the malathion-susceptible MSS strain, while the malathion-resistant near-isogenic line, N-MRS, achieved similar resistance level between genders. Significant synergistic effect of the esterase-inhibitor DEF on resistant houseflies pointed to the important involvement of esterase in this specific malathion resistance. Examination of the carboxylesterase gene MdαE7 in malathion resistant housefly populations found seven, non-synonymous SNP mutations (Ser

Indexed as

MutationAnimalsCarboxylesteraseCholinesterase InhibitorsFemaleHousefliesInsecticide ResistanceInsecticidesInsect ProteinsMalathionMaleCarboxylesteraseCholinesterase InhibitorsInsecticidesInsect ProteinsMalathion

Identifiers

PMID29317643
PMCPMC5760516
OpenAlexW2781725469

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.