ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018
Meis1 Coordinates Cerebellar Granule Cell Development by Regulating Pax6 Transcription, BMP Signaling and Atoh1 Degradation.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 81 citations in OpenAlex.
- Human-biasedLife science alliance · 2026Article
- Disinhibition of cerebellar output by loss of restless legs syndrome-associated gene MEIS1.Current biology : CB · 2026Article
- Meis1 isoform diversity orchestrates neural progenitor differentiation by regulating ATOH1 degradation at distinct subcellular compartments.PLoS biology · 2026Article
- Synthesis and Development of Novel Small-Molecule MEIS2 Inhibitors That Induce Cell Death in Breast Cancer Cells by Targeting the Homeobox Domain.Pharmaceuticals (Basel, Switzerland) · 2026Article
- MTCL2 Is Essential for the Bipolar-to-Multipolar Transition in the Dendrite Extension of Cerebellar Granule Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Elucidating Neurodevelopmental Trajectories in Cancer with Topic Modeling: Revealing Persistent External Granule Layer Lineages in Medulloblastoma.bioRxiv : the preprint server for biology · 2025Article
- Hierarchical regulation of cerebellar neurogenesis by Sin3A-mediated gene repression.bioRxiv : the preprint server for biology · 2025Article
- Global human myeloid replacement with peripheral progenitors induces interferonopathy and neurodegeneration.Research square · 2025Article
- Developmental and adult expression of the Meis2 transcription factor in the central nervous system ofFrontiers in neuroanatomy · 2025Article
- A Single-Cell Transcriptomic Analysis of the Mouse Hippocampus After Voluntary Exercise.Molecular neurobiology · 2024Article
- Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage.Nature communications · 2024Article
- Genetic effects of sequence-conserved enhancer-like elements on human complex traits.Genome biology · 2024Article
- A primate nigrostriatal atlas of neuronal vulnerability and resilience in a model of Parkinson's disease.Nature communications · 2023Article
- Ganglioglioma deep transcriptomics reveals primitive neuroectoderm neural precursor-like population.Acta neuropathologica communications · 2023Article
- Identification of PAX6 and NFAT4 as the Transcriptional Regulators of the Long Noncoding RNA Mrhl in Neuronal Progenitors.Molecular and cellular biology · 2022Article
- Genome-wide analysis identifies Homothorax and Extradenticle as regulators of insulin in Drosophila Insulin-Producing cells.PLoS genetics · 2022Article
- Review
- Meis1 Regulates Nociceptor Development and Behavioral Response to Tactile Stimuli.Frontiers in molecular neuroscience · 2022Article
- Cell-Cell Communication AlterationsFrontiers in aging neuroscience · 2022Article
- Restless legs syndrome.Nature reviews. Disease primers · 2021Review
Corrections and comments
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Authors and funding
15 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cerebellar granule cell precursors (GCPs) and granule cells (GCs) represent good models to study neuronal development. Here, we report that the transcription factor myeloid ectopic viral integration site 1 homolog (Meis1) plays pivotal roles in the regulation of mouse GC development. We found that Meis1 is expressed in GC lineage cells and astrocytes in the cerebellum during development. Targeted disruption of the Meis1 gene specifically in the GC lineage resulted in smaller cerebella with disorganized lobules. Knock-down/knock-out (KO) experiments for Meis1 and
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