Evidence map›Paper›PMID 29316964›Full record

ArticleBMC research notes2018

Genome-wide diversity and runs of homozygosity in the "Braque Français, type Pyrénées" dog breed.

Salvatore Mastrangelo, Filippo Biscarini, Barbara Auzino, Marco Ragatzu, Andrea Spaterna, Roberta Ciampolini

Abstract read
In one paragraph

Article in BMC research notes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Genotypic and phenotypic consequences of domestication in dogs.bioRxiv : the preprint server for biology · 2025
    Article
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  9. Analysis of Genetic Diversity in the Czech Spotted Dog.Animals : an open access journal from MDPI · 2020
    Article
  10. The German Shorthair Pointer Dog Breed (Animals : an open access journal from MDPI · 2020
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Salvatore MastrangeloDipartimento di Scienze Agrarie e Forestali, Università di Palermo, Palermo, Italy.
Filippo BiscariniCNR-IBBA, Via Bassini 15, 20133, Milano, Italy. filippo.biscarini@ibba.cnr.it.ORCID http://orcid.org/0000-0002-3901-2354
Barbara AuzinoDipartimento di Scienze Veterinarie, Università di Pisa, V.le delle Piagge 2, 56124, Pisa, Italy.
Marco RagatzuClub Italiano Braque Français Type Pyrénées, Capalbio, GR, Italy.
Andrea SpaternaScuola di Scienze Mediche Veterinarie, University of Camerino, Matelica, MC, Italy.
Roberta CiampoliniCentro Interuniversitario di Ricerca e di Consulenza sulla Genetica e la Clinica del cane, Matelica, MC, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveBraque Français, type Pyrénées is a French hunting-dog breed whose origin is traced back to old pointing gun-dogs used to assist hunters in finding and retrieving game. This breed is popular in France, but seldom seen elsewhere. Despite the ancient background, the literature on its genetic characterization is surprisingly scarce. A recent study looked into the demography and inbreeding using pedigree records, but there is yet no report on the use of molecular markers in this breed. The aim of this work was to genotype a population of Braque Français, type Pyrénées dogs with the high-density SNP array to study the genomic diversity of the breed.

resultsThe average observed ([Formula: see text]) and expected ([Formula: see text]) heterozygosity were 0.371 ([Formula: see text]) and 0.359 ([Formula: see text]). Effective population size ([Formula: see text]) was 27.5635 runs of homozygosity (ROH) were identified with average length of 2.16 MB. A ROH shared by [Formula: see text] of the dogs was detected at the beginning of chromosome 22. Inbreeding coefficients from marker genotypes were in the range [Formula: see text]. Inbreeding estimated from ROH ([Formula: see text]) had mean [Formula: see text]), with range [0.0526, 0.225]. These results show that the Braque Français, type Pyrénées breed is a relatively inbred population, but with still sufficient genetic variability for conservation and genetic improvement.

Indexed as

HeterozygoteHomozygoteInbreedingAnimalsDogsFemaleFranceGenetic MarkersGenetic VariationGenomeMalePolymorphism, Single NucleotideGenetic MarkersBraque Français, type PyrénéesDogGenetic diversityHeterozygosityInbreedingMolecular markersRuns of homozygositySNP

Identifiers

PMID29316964
PMCPMC5761150

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.