Evidence map›Paper›PMID 29316900›Full record

ArticleBMC public health2018

Epidemiology and factors associated with amoebic liver abscess in northern Sri Lanka.

Selvam Kannathasan, Arumugam Murugananthan, Thirunavukarasu Kumanan, Nilanthi Renuka de Silva, Nadarajah Rajeshkannan, Rashidul Haque, Devika Iddawela

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Amebic liver abscess: An update.World journal of hepatology · 2024
    Review
  7. Amebic liver abscess byWorld journal of clinical cases · 2022
    Review
  8. Review
  9. Amoebic Liver Abscess: A disease native to Oman?Sultan Qaboos University medical journal · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Tropical medicine and health · 2020
    Review
  15. Article
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Selvam KannathasanDepartment of Pathology, Faculty of Medicine, University of Jaffna, Jaffna, Sri Lanka. selvamkannathasan@gmail.com.ORCID 0000-0002-8582-5188
Arumugam MurugananthanDepartment of Pathology, Faculty of Medicine, University of Jaffna, Jaffna, Sri Lanka.
Thirunavukarasu KumananDepartment of Medicine, Faculty of Medicine, University of Jaffna, Jaffna, Sri Lanka.
Nilanthi Renuka de SilvaDepartment of Parasitology, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.
Nadarajah RajeshkannanSt Johns' Park Medical Center, Sydney, Australia.
Rashidul HaqueInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Devika IddawelaDepartment of Parasitology, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.
University of Jaffna · LKInternational Centre for Diarrhoeal Disease Research · BDUniversity of Kelaniya · LKUniversity of Peradeniya · LK

Funding

World Bank Group JFN /O-Med/ N8
6 · The paper itself

Abstract

backgroundClinically diagnosed amoebic liver abscess (ALA) caused by Entamoeba histolytica has been an important public health problem in Jaffna district, northern Sri Lanka for last three decades. In order to draw up a control strategy for elimination of this condition, knowledge of its epidemiology and factors associated with this condition in the local context is vital.

methodsAll clinically diagnosed ALA patients admitted to the Teaching Hospital, Jaffna during the study period were included in the study and the data were collected using an interviewer administered questionnaire. One hundred blood samples from randomly selected toddy (a local alcoholic drink consisting of the fermented sap of the Palmyrah palm) consumers and 200 toddy samples were collected. Toddy samples were cultured in Robinson's medium to establish the presence of Entamoeba histolytica in the sample. Climatic data and the total toddy sales in the district were obtained from the Meteorological and Excise Departments respectively. A sub group of randomly selected 100 patients were compared with 100 toddy consumers who were negative for E. histolytica antibody to explore the potential risk factors.

resultsBetween July 2012 and July 2015, 346 of 367 ALA patients were enrolled in this study. Almost all patients (98.6%) were males with a history of heavy consumption of alcohol (100%). Almost all (94.2%) were within the age group 31-50 years. None of the cultured toddy samples grew E. histolytica. The monthly incidence of disease peaked in the dry season, matching the total toddy sales in the district. Age, type of alcohol and frequency of drinking were identified as potential risk factors whereas frequency of alcohol consumption and type of alcohol (consuming toddy and arrack) were identified as the independent risk factors. Moreover, the knowledge, attitude and practices towards ALA were poor among participants and the control group.

conclusionsThough the number of cases has declined in recent years, ALA still remains as an important public health problem in Jaffna district. The transmission route of E. histolytica leading to ALA has to be further explored. Moreover, greater awareness among the public who are at risk would be beneficial in order to eliminate the disease.

Indexed as

AdultAlcohol DrinkingEntamoeba histolyticaFemaleHumansLiver Abscess, AmebicMaleMiddle AgedRisk FactorsSri LankaSurveys and QuestionnairesAmoebiasisAmoebic liver abscessEntamoeba histolyticaSri Lanka

Identifiers

PMID29316900
PMCPMC5761098
OpenAlexW2782545312

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.