Evidence map›Paper›PMID 29316889›Full record

SynthesisBMC family practice2018

A systematic review of chronic disease management interventions in primary care.

Rebecca Reynolds, Sarah Dennis, Iqbal Hasan, Jan Slewa, Winnie Chen, David Tian, Sangeetha Bobba, Nicholas Zwar

Registry-linked trialOpen access · goldAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC family practice, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07628647 (Pilot Study of the Living Well With Brain Cancer Intervention), which is not on this map. Cited by 221 papers, 22 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
221citing papers in PubMed, 22 pooled it
38.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07628647 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Pilot Study of the Living Well With Brain Cancer Intervention

TypeinterventionalSponsorUniversity of Colorado, DenverRan2026 to 2027Enrolled64ConditionsBrain CancerArmsGroup Self-Management Sessions, Educational Materials Only
3 · Its place in the literature

Who cites it

221 citing papers in PubMed, 22 syntheses or guidelines pooled it, 605 citations in OpenAlex.

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  3. The social determinants of health-related quality of life among people with chronic disease: a systematic literature review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
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161 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Rebecca ReynoldsUNSW, Sydney, Australia.
Sarah DennisUniversity of Sydney, Camperdown, Australia.
Iqbal HasanUNSW, Sydney, Australia.
Jan SlewaUNSW, Sydney, Australia.
Winnie ChenUNSW, Sydney, Australia.
David TianUNSW, Sydney, Australia.
Sangeetha BobbaUNSW, Sydney, Australia.
Nicholas ZwarUNSW, Sydney, Australia. nzwar@uow.edu.au.ORCID 0000-0001-6462-9121
UNSW Sydney · AUThe University of Sydney · AUUniversity of Wollongong · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrimary and community care are key settings for the effective management of long term conditions. We aimed to evaluate the pattern of health outcomes in chronic disease management interventions for adults with physical health problems implemented in primary or community care settings.

methodsThe methods were based on our previous review published in 2006. We performed database searches for articles published from 2006 to 2014 and conducted a systematic review with narrative synthesis using the Cochrane Effective Practice and Organisation of Care taxonomy to classify interventions and outcomes. The interventions were mapped to Chronic Care Model elements. The pattern of outcomes related to interventions was summarized by frequency of statistically significant improvements in health care provision and patient outcomes.

resultsA total of 9589 journal articles were retrieved from database searches and snowballing. After screening and verification, 165 articles that detailed 157 studies were included. There were few studies with Health Care Organization (1.9% of studies) or Community Resources (0.6% of studies) as the primary intervention element. Self-Management Support interventions (45.8% of studies) most frequently resulted in improvements in patient-level outcomes. Delivery System Design interventions (22.6% of studies) showed benefits in both professional and patient-level outcomes for a narrow range of conditions. Decision Support interventions (21.3% of studies) had impact limited to professional-level outcomes, in particular use of medications. The small number of studies of Clinical Information System interventions (8.9%) showed benefits for both professional- and patient-level outcomes.

conclusionsThe published literature has expanded substantially since 2006. This review confirms that Self-Management Support is the most frequent Chronic Care Model intervention that is associated with statistically significant improvements, predominately for diabetes and hypertension.

Indexed as

Chronic DiseaseHumansPatient Care ManagementPatient Outcome AssessmentPrimary Health CareSelf-ManagementArthritisCardiovascularChronic careDiabetesDisease management/care managementEndocrinologyMusculoskeletal/connective tissueRespiratory systemSystematic review

Identifiers

PMID29316889
PMCPMC5759778
OpenAlexW2784104515

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.