Evidence map›Paper›PMID 29316715›Full record

Trial reportInternational journal of molecular sciences2018

Twelve Weeks of Medium-Intensity Exercise Therapy Affects the Lipoprotein Profile of Multiple Sclerosis Patients.

Winde Jorissen, Tim Vanmierlo, Inez Wens, Veerle Somers, Bart Van Wijmeersch, Jeroen F Bogie, Alan T Remaley, Bert O Eijnde, Jerome J A Hendriks

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Winde JorissenBIOMED, School of Life Sciences, Hasselt University, 3590 Diepenbeek, Belgium. winde.jorissen@uhasselt.be.
Tim VanmierloBIOMED, School of Life Sciences, Hasselt University, 3590 Diepenbeek, Belgium. tim.vanmierlo@uhasselt.be.
Inez WensREVAL Rehabilitation Research Center, BIOMED Biomedical Research Institute, Faculty of Medicine and Life Sciences, Hasselt University, 3590 Diepenbeek, Belgium. inez.wens@uhasselt.be.
Veerle SomersBIOMED, School of Life Sciences, Hasselt University, 3590 Diepenbeek, Belgium. veerle.somers@uhasselt.be.ORCID 0000-0002-4950-8724
Bart Van WijmeerschRevalidation and MS Center, 3900 Overpelt, Belgium. bart.vanwijmeersch@uhasselt.be.
Jeroen F BogieBIOMED, School of Life Sciences, Hasselt University, 3590 Diepenbeek, Belgium. jeroen.bogie@uhasselt.be.
Alan T RemaleyClinical Center, Department of Laboratory Medicine, National Institutes of Health Clinical Center (NIH), Bethesda, MD 20814, USA. Alan.Remaley@nih.gov.
Bert O EijndeREVAL Rehabilitation Research Center, BIOMED Biomedical Research Institute, Faculty of Medicine and Life Sciences, Hasselt University, 3590 Diepenbeek, Belgium. bert.opteijnde@uhasselt.be.
Jerome J A HendriksBIOMED, School of Life Sciences, Hasselt University, 3590 Diepenbeek, Belgium. jerome.hendriks@uhasselt.be.ORCID 0000-0002-7717-8582
Hasselt University · BENational Institutes of Health Clinical Center · USNational MS Center Melsbroek

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple sclerosis (MS) is an inflammatory auto-immune disease of the central nervous system (CNS). Serum glucose alterations and impaired glucose tolerance (IGT) are reported in MS patients, and are commonly associated with the development of cardio-metabolic co-morbidities. We previously found that a subgroup of MS patients shows alterations in their lipoprotein profile that are similar to a pre-cardiovascular risk profile. In addition, we showed that a high-intensity exercise training has a positive effect on IGT in MS patients. In this study, we hypothesize that exercise training positively influences the lipoprotein profile of MS patients. To this end, we performed a pilot study and determined the lipoprotein profile before (controls,

Indexed as

Blood GlucoseCardiovascular DiseasesCholesterol, LDLExercise TherapyFemaleHigh-Intensity Interval TrainingHumansMaleMiddle AgedMultiple SclerosisBlood GlucoseCholesterol, LDLcholesterollipoproteinsmultiple sclerosistraining exercise

Identifiers

PMID29316715
PMCPMC5796142
OpenAlexW2783654974

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.