ArticleArthritis care & research2018
Changes in Pain Sensitization After Bariatric Surgery.
Article in Arthritis care & research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 50 citations in OpenAlex.
- Osteoarthritis as a systemic disease.Nature reviews. Rheumatology · 2026Review
- Dampened inflammation and reduced risk of osteoarthritis among non-industrialized societies.Osteoarthritis and cartilage · 2026Review
- Opioid Usage, Disposal Methods, and NSAID Usage After Hip Arthroscopy.Orthopaedic journal of sports medicine · 2025Article
- Changes in Widespread Pain After Surgical Weight Loss in Racialized Adults: A Secondary Analysis From a 2-Year Longitudinal Study.The journal of pain · 2024Article
- Obesity and the risk of multiple or severe frequent knee pain episodes: a 4-year follow-up of the ELSA-Brasil MSK cohort.International journal of obesity (2005) · 2024Article
- Associations between chronic widespread pain, pressure pain thresholds, leptin, and metabolic factors in individuals with knee pain.BMC musculoskeletal disorders · 2023Article
- Polygenic Contributions to Chronic Overlapping Pain Conditions in a Large Electronic Health Record Sample.The journal of pain · 2023Article
- Prescriptions for pain medication before and after bariatric surgery.Surgical endoscopy · 2022Article
- Associations of Body Mass Index With Pain and the Mediating Role of Inflammatory Biomarkers in People With Hand Osteoarthritis.Arthritis & rheumatology (Hoboken, N.J.) · 2022Article
- Early Relationships of a Low-Energy Diet With Symptoms of Fibromyalgia.ACR open rheumatology · 2022Article
- Emerging pharmaceutical therapies for osteoarthritis.Nature reviews. Rheumatology · 2020Review
- The relation of peripheral and central sensitization to muscle co-contraction: the MOST study.Osteoarthritis and cartilage · 2020Article
- Mediating Role of Bone Marrow Lesions, Synovitis, Pain Sensitization, and Depressive Symptoms on Knee Pain Improvement Following Substantial Weight Loss.Arthritis & rheumatology (Hoboken, N.J.) · 2020Article
- Article
- Modern-day environmental factors in the pathogenesis of osteoarthritis.Nature reviews. Rheumatology · 2018Review
- Changes in the structural features of osteoarthritis in a year of weight loss.Osteoarthritis and cartilage · 2018Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo evaluate changes in pain (at the knee and elsewhere) and pain sensitization in obese subjects with knee pain who were having bariatric surgery compared with similarly obese individuals who were undergoing medical management.
methodsThis study included a cohort of subjects who were having bariatric surgery and those undergoing medical management. Knee pain severity of the more painful knee (index knee) was assessed at baseline and at 12 months using the Western Ontario and McMaster Universities Osteoarthritis Index. The pressure pain threshold (PPT) was evaluated at the index patella and the right wrist. Low patella PPT may reflect peripheral and/or central sensitization, and low wrist PPT may reflect central sensitization. The mean change in measures of pain and pain sensitization was analyzed in the surgery and medical management groups separately.
resultsA total of 45 subjects in the surgery group and 22 in the medical management group completed baseline and follow-up visits. The mean weight loss was 32.7 kg (29.0%) and 4.6 kg (4.1%) in the surgery and medical management groups, respectively. Knee pain decreased only in the surgery group, in which the PPT at the patella improved by 38.5% (P = 0.0007) and at the wrist by 30.9% (P = 0.005). There was no significant change in PPT in the medical management group.
conclusionPersons who underwent bariatric surgery experienced an improvement in pain sensitization, reflected by improvements in PPT. This improvement was observed not only at the patella, but also at the wrist, suggesting that central sensitization improved after bariatric surgery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.