Evidence map›Paper›PMID 29316363›Full record

ReviewAdvanced healthcare materials2018

Exploiting Advanced Hydrogel Technologies to Address Key Challenges in Regenerative Medicine.

Daniel A Foyt, Michael D A Norman, Tracy T L Yu, Eileen Gentleman

Open access · hybridAbstract readReview
In one paragraph

Review in Advanced healthcare materials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 143 citations in OpenAlex.

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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Daniel A FoytCentre for Craniofacial and Regenerative Biology, King's College London, London, SE1 9RT, UK.
Michael D A NormanCentre for Craniofacial and Regenerative Biology, King's College London, London, SE1 9RT, UK.
Tracy T L YuCentre for Craniofacial and Regenerative Biology, King's College London, London, SE1 9RT, UK.
Eileen GentlemanCentre for Craniofacial and Regenerative Biology, King's College London, London, SE1 9RT, UK.ORCID 0000-0003-0447-5137
King's College London · GB

Funding

Biotechnology and Biological Sciences Research CouncilWellcome Trust 093687
6 · The paper itself

Abstract

Regenerative medicine aims to tackle a panoply of challenges from repairing focal damage to articular cartilage to preventing pathological tissue remodeling after myocardial infarction. Hydrogels are water-swollen networks formed from synthetic or naturally derived polymers and are emerging as important tools to address these challenges. Recent advances in hydrogel chemistries are enabling researchers to create hydrogels that can act as 3D ex vivo tissue models, allowing them to explore fundamental questions in cell biology by replicating tissues' dynamic and nonlinear physical properties. Enabled by cutting edge techniques such as 3D bioprinting, cell-laden hydrogels are also being developed with highly controlled tissue-specific architectures, vasculature, and biological functions that together can direct tissue repair. Moreover, advanced in situ forming and acellular hydrogels are increasingly finding use as delivery vehicles for bioactive compounds and in mediating host cell response. Here, advances in the design and fabrication of hydrogels for regenerative medicine are reviewed. It is also addressed how controlled chemistries are allowing for precise engineering of spatial and time-dependent properties in hydrogels with a look to how these materials will eventually translate to clinical applications.

Indexed as

Printing, Three-DimensionalAnimalsBioprintingHumansHydrogelsRegenerative MedicineHydrogelsadvanced therapiesbiomaterialsbioprintinghydrogelsregenerative medicinetissue engineering

Identifiers

PMID29316363
PMCPMC5922416
OpenAlexW2784276418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.