Evidence map›Paper›PMID 29315676›Full record

ArticleMuscle & nerve2018

Aging impairs regulation of ryanodine receptors from extensor digitorum longus but not soleus muscles.

Angela J Gaboardi, Jochen Kressler, Teresa K Snow, Edward M Balog

Abstract read
In one paragraph

Article in Muscle & nerve, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Angela J GaboardiSchool of Applied Physiology, Georgia Institute of Technology, 281 Ferst Drive, Atlanta, GA, 30332, USA.
Jochen KresslerExercise and Nutritional Sciences Department, School of Health and Human Services, San Diego State University, 5500 Campanile Dr., San Diego, CA 92182, USA.
Teresa K SnowSchool of Applied Physiology, Georgia Institute of Technology, 281 Ferst Drive, Atlanta, GA, 30332, USA.
Edward M BalogSchool of Applied Physiology, Georgia Institute of Technology, 281 Ferst Drive, Atlanta, GA, 30332, USA.
Georgia Institute of Technology · USSan Diego State University · US

Funding

SR Calcium Release Channel Regulation in Aging MuscleR03AG023902 · NIA · GEORGIA INSTITUTE OF TECHNOLOGY · PI BALOG, EDWARD M · 2005 to 2006
$148k
NIA NIH HHS R03 AG023902
6 · The paper itself

Abstract

introductionBecause impaired excitation-contraction coupling and reduced sarcoplasmic reticulum (SR) Ca

methods[

resultsAging reduced maximal Ca DISCUSSION: In aged fast-twitch muscle, impaired RyR1 Ca

Indexed as

AgingAnimalsCalcium SignalingExcitation Contraction CouplingMaleMuscle, SkeletalRatsRats, Inbred F344Ryanodine Receptor Calcium Release ChannelSarcoplasmic ReticulumRyanodine Receptor Calcium Release Channelagingcalciumcalmodulinexcitation-contraction couplingryanodine receptorsarcoplasmic reticulumskeletal muscle

Identifiers

PMID29315676
PMCPMC5951731
OpenAlexW2783116247

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.