Evidence map›Paper›PMID 29315674›Full record

ArticleHepatology (Baltimore, Md.)2018

Is miR-21 a potent target for liver fibrosis?

Sanchuan Lai, Yasuko Iwakiri

Abstract readEditorialComment
In one paragraph

Article in Hepatology (Baltimore, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Article
  3. Serum non-coding RNAs for diagnosis and stage of liver fibrosis.Journal of clinical laboratory analysis · 2022
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Longitudinal analysis of serum microRNAs as predictors of cirrhosis regression during treatment of hepatitis B virus infection.Liver international : official journal of the International Association for the Study of the Liver · 2020
    Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Sanchuan LaiSection of Digestive Diseases, Yale University School of Medicine, New Haven, CT.
Yasuko IwakiriSection of Digestive Diseases, Yale University School of Medicine, New Haven, CT.

Funding

The role of Kupffer cells in alcohol-induced liver diseaseR01AA025342 · NIAAA · YALE UNIVERSITY · PI IWAKIRI, YASUKO · 2017 to 2021
$1.9M
Mechanisms of Alcohol-Induced Hepatic OsteodystrophyR21AA023607 · NIAAA · YALE UNIVERSITY · PI IWAKIRI, YASUKO · 2016 to 2017
$440k
Alcohol metabolism in liver sinusoidal endothelial cellsR21AA023599 · NIAAA · YALE UNIVERSITY · PI IWAKIRI, YASUKO · 2015 to 2016
$437k
NIAAA NIH HHS R01 AA025342NIAAA NIH HHS R21 AA023599NIAAA NIH HHS R21 AA023607
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hepatic Stellate CellsLiver CirrhosisHumansMicroRNAsMicroRNAsMIRN21 microRNA, human

Identifiers

PMID29315674
PMCPMC5992001

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.