ArticlePloS one2018
Transjugular intrahepatic portosystemic shunts (TIPS) for the prevention of variceal re-bleeding - A two decades experience.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 29 citations in OpenAlex.
- Alcohol Use After TIPS Implantation Significantly Increases the Risk of ACLF and Liver-Related Death.United European gastroenterology journal · 2026Article
- Transjugular intrahepatic portosystemic shunt with ePTFE-covered stentgrafts: incidence and predictors of shunt dysfunction.Insights into imaging · 2025Article
- [Position paper for the standardized use of transjugular intrahepatic portosystemic shunt (TIPS) in adults].Zeitschrift fur Gastroenterologie · 2025Article
- Shunt dysfunction and mortality after transjugular intrahepatic portosystemic shunt (TIPS) in patients with portal hypertension.Insights into imaging · 2024Article
- Covered Transjugular Intrahepatic Portosystemic Shunt Improves Hypersplenism-Associated Cytopenia in Cirrhosis.Digestive diseases and sciences · 2022Article
- 25 years of experience with transjugular intrahepatic portosystemic shunt (TIPS): changes in patient selection and procedural aspects.Insights into imaging · 2022Article
- Distinct prognostic value of different portal hypertension-associated features in patients with primary biliary cholangitis.Journal of gastroenterology · 2022Article
- Diagnostic Value of Contrast-Enhanced Ultrasound for Evaluation of Transjugular Intrahepatic Portosystemic Shunt Perfusion.Diagnostics (Basel, Switzerland) · 2021Article
- Perceptions on the management of varices and on the use of albumin in patients with cirrhosis among GI specialists in Austria.Wiener klinische Wochenschrift · 2021Article
- Patterns of acute decompensation in hospitalized patients with cirrhosis and course of acute-on-chronic liver failure.United European gastroenterology journal · 2021Article
- TIPSRadiology and oncology · 2021Article
- MRI-defined sarcopenia predicts mortality in patients with chronic liver disease.Liver international : official journal of the International Association for the Study of the Liver · 2020Article
- Hospital readmission following transjugular intrahepatic portosystemic shunt: a 14-year single-center experience.Gastroenterology report · 2020Article
- Emergent Transjugular Intrahepatic Portosystemic Shunt Creation in Acute Variceal Bleeding.Seminars in interventional radiology · 2020Review
- Clinical effect of single covered stent and double covered stent on TIPS in the treatment of hemorrhage due to rupture of esophageal and gastric varices in cirrhosis and its influence on immune function.Experimental and therapeutic medicine · 2019Article
- The value of different CT-based methods for diagnosing low muscle mass and predicting mortality in patients with cirrhosis.Liver international : official journal of the International Association for the Study of the Liver · 2019Article
- Emergency Transjugular Intrahepatic Portosystemic Shunt: an Effective and Safe Treatment for Uncontrolled Variceal Bleeding.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2019Article
- A case of fatal cutaneous caput medusae hemorrhage.Clinical case reports · 2019Article
- Recanalizing the Path Forward: Revisiting the Role of Portal Vein Recanalization With Transjugular Intrahepatic Portosystemic Shunt in Cirrhotic Portal Vein Thrombosis.Journal of clinical and experimental hepatologyArticle
Corrections and comments
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Authors and funding
17 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsTransjugular intrahepatic portosystemic shunts (TIPS) are used in patients with cirrhosis for the prevention of variceal rebleeding.
methodsWe retrospectively evaluated re-bleeding rate, patency, mortality, and transplant-free survival (TFS) in cirrhotic patients receiving TIPS implantation for variceal bleeding between 1994-2014.
results286 patients received TIPS (n = 119 bare metal stents, n = 167 polytetrafluorethylene (PTFE)-covered stents) for prevention of variceal re-bleeding. Mean age was 55.1 years, median MELD was 11.8, and the main etiology of cirrhosis was alcoholic liver disease (70%). Median follow-up was 821 days. 67 patients (23%) experienced at least one re-bleeding event. Patients with PTFE-TIPS were at significantly lower risk for variceal re-bleeding than patients with bare metal stents (14% vs. 37%, OR:0.259; p<0.001) and had less need for stent revision (21% vs. 37%; p = 0.024). Patients with PTFE stent grafts showed lower mortality than patients with bare stents after 1 year (19% vs. 31%, p = 0.020) and 2 years (29% vs. 40%; p = 0.041) after TIPS implantation. Occurrence of hepatic encephalopathy after TIPS was similar between groups (20% vs. 24%, p = 0.449).
conclusionsPTFE-TIPS were more effective at preventing variceal re-bleeding than bare metal stents due to better patency. Since this tended to translate in improved survival, only covered stents should be implemented for bleeding prophylaxis when TIPS is indicated.
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