Evidence map›Paper›PMID 29315301›Full record

ArticlePLoS biology2018

Population genomics of Mesolithic Scandinavia: Investigating early postglacial migration routes and high-latitude adaptation.

Torsten Günther, Helena Malmström, Emma M Svensson, Ayça Omrak, Federico Sánchez-Quinto, Gülşah M Kılınç, Maja Krzewińska, Gunilla Eriksson, Magdalena Fraser, Hanna Edlund and 17 more

Open access · goldAbstract readHistorical Article
In one paragraph

Article in PLoS biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed
20.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

101 citing papers in PubMed, 256 citations in OpenAlex.

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  8. Ancient environmental genome reveals a migratory brown bear individual in Early Holocene Scandinavia.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  11. Global patterns of natural selection inferred using ancient DNA.bioRxiv : the preprint server for biology · 2026
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  12. Polygenic prediction of human complex traits using ancient DNA.Current opinion in genetics & development · 2025
    Review
  13. Article
  14. Article
  15. Article
  16. Inference of human pigmentation from ancient DNA by genotype likelihoods.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  17. Article
  18. Article
  19. Why humans evolved blue eyes.Frontiers in psychology · 2025
    Article
  20. Article

41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

27 authors at 10 institutions in 7 countries.

Torsten GüntherDepartment of Organismal Biology, Uppsala University, Uppsala, Sweden.ORCID 0000-0001-9460-390X
Helena MalmströmDepartment of Organismal Biology, Uppsala University, Uppsala, Sweden.
Emma M SvenssonDepartment of Organismal Biology, Uppsala University, Uppsala, Sweden.
Ayça OmrakDepartment of Archaeology and Classical Studies, Stockholm University, Stockholm, Sweden.
Federico Sánchez-QuintoDepartment of Organismal Biology, Uppsala University, Uppsala, Sweden.
Gülşah M KılınçDepartment of Organismal Biology, Uppsala University, Uppsala, Sweden.
Maja KrzewińskaDepartment of Archaeology and Classical Studies, Stockholm University, Stockholm, Sweden.
Gunilla ErikssonDepartment of Archaeology and Classical Studies, Stockholm University, Stockholm, Sweden.
Magdalena FraserDepartment of Organismal Biology, Uppsala University, Uppsala, Sweden.
Hanna EdlundDepartment of Organismal Biology, Uppsala University, Uppsala, Sweden.
Arielle R MuntersDepartment of Organismal Biology, Uppsala University, Uppsala, Sweden.
Alexandra CoutinhoDepartment of Organismal Biology, Uppsala University, Uppsala, Sweden.
Luciana G SimõesDepartment of Organismal Biology, Uppsala University, Uppsala, Sweden.
Mário VicenteDepartment of Organismal Biology, Uppsala University, Uppsala, Sweden.
Anders SjölanderDepartment of Organismal Biology, Uppsala University, Uppsala, Sweden.
Berit Jansen SellevoldNorwegian Institute for Cultural Heritage Research, Oslo, Norway.
Roger JørgensenTromsø University Museum, University of Tromsø-The Arctic University of Norway, Tromsø, Norway.
Peter ClaesDepartment of Electrical Engineering, Center for Processing Speech and Images, Katholieke Universiteit Leuven, Leuven, Belgium.
Mark D ShriverDepartment of Anthropology, Penn State University, State College, Pennsylvania, United States of America.
Cristina ValdioseraDepartment of Archaeology and History, La Trobe University, Melbourne, Australia.
Mihai G NeteaDepartment of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.
Jan ApelDepartment of Archaeology and Ancient History, Lund University, Lund, Sweden.
Kerstin LidénDepartment of Archaeology and Classical Studies, Stockholm University, Stockholm, Sweden.
Birgitte SkarDepartment of Archaeology and Cultural History, Norwegian University of Science and Technology University Museum, Trondheim, Norway.
Jan StoråDepartment of Archaeology and Classical Studies, Stockholm University, Stockholm, Sweden.
Anders GötherströmDepartment of Archaeology and Classical Studies, Stockholm University, Stockholm, Sweden.
Mattias JakobssonDepartment of Organismal Biology, Uppsala University, Uppsala, Sweden.
Uppsala University · SEStockholm University · SEKU Leuven · BELa Trobe University · AULund University · SENorwegian Institute for Cultural Heritage Research · NONorwegian University of Science and Technology · NOPennsylvania State University · USRadboud University Nijmegen · NLUiT The Arctic University of Norway · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Scandinavia was one of the last geographic areas in Europe to become habitable for humans after the Last Glacial Maximum (LGM). However, the routes and genetic composition of these postglacial migrants remain unclear. We sequenced the genomes, up to 57× coverage, of seven hunter-gatherers excavated across Scandinavia and dated from 9,500-6,000 years before present (BP). Surprisingly, among the Scandinavian Mesolithic individuals, the genetic data display an east-west genetic gradient that opposes the pattern seen in other parts of Mesolithic Europe. Our results suggest two different early postglacial migrations into Scandinavia: initially from the south, and later, from the northeast. The latter followed the ice-free Norwegian north Atlantic coast, along which novel and advanced pressure-blade stone-tool techniques may have spread. These two groups met and mixed in Scandinavia, creating a genetically diverse population, which shows patterns of genetic adaptation to high latitude environments. These potential adaptations include high frequencies of low pigmentation variants and a gene region associated with physical performance, which shows strong continuity into modern-day northern Europeans.

Indexed as

Adaptation, PhysiologicalEuropeFemaleFossilsGenetics, PopulationGenetic VariationHistory, AncientHuman MigrationHumansMaleMembrane ProteinsMetagenomicsPigmentationScandinavian and Nordic CountriesWhite PeopleMembrane ProteinsTMEM131L protein, human

Identifiers

PMID29315301
PMCPMC5760011
OpenAlexW2783113319

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.