Evidence map›Paper›PMID 29315233›Full record

ArticleInternational journal of molecular sciences2018

Dissecting Time- from Tumor-Related Gene Expression Variability in Bilateral Breast Cancer.

Maurizio Callari, Matteo Dugo, Patrizia Miodini, Silvia Veneroni, Giampaolo Bianchini, Maria Grazia Daidone, Vera Cappelletti

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Maurizio CallariDepartment of Applied Research and Technical Development, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milano, Italy. Maurizio.Callari@cruk.cam.ac.uk.ORCID 0000-0001-5239-0918
Matteo DugoDepartment of Applied Research and Technical Development, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milano, Italy. matteo.dugo@istitutotumori.mi.it.
Patrizia MiodiniDepartment of Applied Research and Technical Development, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milano, Italy. patrizia.miodini@istitutotumori.mi.it.
Silvia VeneroniDepartment of Applied Research and Technical Development, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milano, Italy. silvia.veneroni@istitutotumori.mi.it.
Giampaolo BianchiniDepartment of Medical Oncology, IRCCS Ospedale San Raffaele, 20132 Milano, Italy. bianchini.giampaolo@hsr.it.
Maria Grazia DaidoneDepartment of Applied Research and Technical Development, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milano, Italy. mariagrazia.daidone@istitutotumori.mi.it.ORCID 0000-0002-4786-1321
Vera CappellettiDepartment of Applied Research and Technical Development, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milano, Italy. vera.cappelletti@istitutotumori.mi.it.ORCID 0000-0002-9709-0676
Fondazione IRCCS Istituto Nazionale dei Tumori · ITIRCCS Ospedale San Raffaele · ITUniversity of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metachronous (MBC) and synchronous bilateral breast tumors (SBC) are mostly distinct primaries, whereas paired primaries and their local recurrences (LRC) share a common origin. Intra-pair gene expression variability in MBC, SBC, and LRC derives from time/tumor microenvironment-related and tumor genetic background-related factors and pairs represents an ideal model for trying to dissect tumor-related from microenvironment-related variability. Pairs of tumors derived from women with SBC (

Indexed as

TranscriptomeAdultAgedAged, 80 and overAnalysis of VarianceBreast NeoplasmsFemaleHumansMiddle AgedNeoplasm Recurrence, LocalNeoplasms, Multiple PrimaryNeoplasms, Second PrimaryRisk FactorsTumor MicroenvironmentBilateral breast cancergene expression profileslocal relapsesPAM50stromal genestumor microenvironment

Identifiers

PMID29315233
PMCPMC5796145
OpenAlexW2784116382

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.