Trial reportMedicine and science in sports and exercise2018
Novel Methods for Reporting of Exercise Dose and Adherence: An Exploratory Analysis.
Trial report in Medicine and science in sports and exercise, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Retention rates and reasons for non-retention in exercise oncology trials in the post-treatment phase-a systematic review.Journal of cancer survivorship : research and practice · 2025Pooled it
- Effect of home-based exercise prehabilitation on postoperative outcomes in colorectal cancer surgery: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Pooled it
- Inclusivity in prostate cancer and exercise research: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Pooled it
- Attention to principles of exercise training: an updated systematic review of randomized controlled trials in cancers other than breast and prostate.BMC cancer · 2021Pooled it
- Pooled it
- A systematic review exploring the evidence reported to underpin exercise dose in clinical trials of rheumatoid arthritis.Rheumatology (Oxford, England) · 2020Pooled it
- Exercise and Nutrition Interventions in Patients with Head and Neck Cancer during Curative Treatment: A Systematic Review and Meta-Analysis.Nutrients · 2020Pooled it
- Exercise training for advanced lung cancer.The Cochrane database of systematic reviews · 2019Pooled it
- Effectiveness of an educational intervention based on the common-sense model of self-regulation for lung cancer patients after thoracoscopic surgery.Scientific reports · 2025Trial
- Effects of aerobic exercise on late effects and quality of life in long-term breast cancer survivors: a randomized controlled trial.JNCI cancer spectrum · 2025Trial
- A Co-clinical Trial of Exercise Therapy in Breast Cancer Prevention.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025Trial
- Effects of Different Training Intensity Distributions on Endurance Capacity in Breast and Prostate Cancer Survivors: A Randomized Controlled Trial.European journal of sport science · 2025Trial
- Trial
- Prescription-based health education integrating functional movement screening: a controlled trial in Chinese university students.Frontiers in public health · 2025Trial
- Effects of Standard Tai Chi on Exercise Capacity and Mental Health in Exercise-Deprived Overweight/Obese Adults and Assessment of Participant Adherence.Chinese journal of integrative medicine · 2024Trial
- Effect of Preoperative Home-Based Exercise Training on Quality of Life After Lung Cancer Surgery: A Multicenter Randomized Controlled Trial.Annals of surgical oncology · 2024Trial
- Timing of exercise therapy when initiating adjuvant chemotherapy for breast cancer: a randomized trial.European heart journal · 2023Trial
- Feasibility of supervised telehealth exercise for patients with advanced melanoma receiving checkpoint inhibitor therapy.Cancer medicine · 2023Trial
- Group-Based and Individually Delivered LiFE: Content Evaluation and Predictors of Training Response - A Dose-Response Analysis.Clinical interventions in aging · 2022Trial
- Effects and tolerability of exercise therapy modality on cardiorespiratory fitness in lung cancer: a randomized controlled trial.Journal of cachexia, sarcopenia and muscle · 2021Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
purposeThe purpose of this study was to explore whether methods adapted from oncology pharmacological trials have utility in reporting adherence (tolerability) of exercise treatment in cancer.
methodsUsing a retrospective analysis of a randomized trial, 25 prostate cancer patients received an aerobic training regimen of 72 supervised treadmill walking sessions delivered thrice weekly between 55% and 100% of exercise capacity for 24 consecutive weeks. Treatment adherence (tolerability) was assessed using conventional (lost to follow-up and attendance) and exploratory (e.g., permanent discontinuation, dose modification, and relative dose intensity) outcomes.
resultsThe mean total cumulative "planned" and "completed" dose was 200.7 ± 47.6 and 153.8 ± 68.8 MET·h, respectively, equating to a mean relative dose intensity of 77% ± 24%. Two patients (8%) were lost to follow-up, and mean attendance was 79%. A total of 6 (24%) of 25 patients permanently discontinued aerobic training before week 24. Aerobic training was interrupted (missing ≥3 consecutive sessions) or dose reduced in a total of 11 (44%) and 24 (96%) patients, respectively; a total 185 (10%) of 1800 training sessions required dose reduction owing to both health-related (all nonserious) and non-health-related adverse events. Eighteen (72%) patients required at least one session to be terminated early; a total of 59 (3%) sessions required early termination.
conclusionsNovel methods for the conduct and reporting of exercise treatment adherence and tolerability may provide important information beyond conventional metrics in patients with cancer.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.