ArticleAddiction biology2019
Validation of a behavioral economic purchase task for assessing drug abuse liability.
Article in Addiction biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Sensitivity of hypothetical purchase task indices when studying substance use: A systematic literature review.Preventive medicine · 2019Pooled it
- Mirtazapine reduces hypothetical methamphetamine demand in humans.Drug and alcohol dependence · 2025Trial
- The Blinded-Dose Purchase Task: assessing hypothetical demand based on cocaine, methamphetamine, and alcohol administration.Psychopharmacology · 2023Trial
- The use of behavioral economic demand in human abuse potential assessment: A review and recommendations for future testing.Experimental and clinical psychopharmacology · 2026Article
- Assessing the abuse liability of U.S. Food and Drug Administration-authorized electronic nicotine delivery systems: Impact of nicotine flux, flavor, and menthol cigarette smoking status.Experimental and clinical psychopharmacology · 2026Article
- The Effects of Orexin Receptor Antagonism During Early Withdrawal in Stimulant Use Disorder: Protocol for a Proof-of-Concept Study.JMIR research protocols · 2026Article
- Acute Stress Effect on Delay Discounting and Cannabis Demand Among Individuals Endorsing High-Frequency Cannabis Use.Cannabis (Albuquerque, N.M.) · 2025Article
- Dose by design: How limits on nicotine flux and puff duration affect the abuse liability of electronic nicotine delivery systems.Drug and alcohol dependence · 2025Article
- Human laboratory models of reward in substance use disorder.Pharmacology, biochemistry, and behavior · 2024Review
- Behavioral economic relationship between cannabis and cigarettes: Evidence from hypothetical purchase tasks.The International journal on drug policy · 2023Article
- A Brief Introduction to Human Behavioral Pharmacology: Methods, Design Considerations and Ethics.Perspectives on behavior science · 2022Article
- Behavioral economic assessment of abuse liability for Black & Mild cigar flavors among young adults.Experimental and clinical psychopharmacology · 2022Article
- New directions in modelling dysregulated reward seeking for food and drugs.Neuroscience and biobehavioral reviews · 2022Review
- Effect of e-cigarette advertisement themes on hypothetical e-cigarette purchasing in price-responsive adolescents.Addiction (Abingdon, England) · 2020Article
- Evaluating the co-use of opioids and cannabis for pain among current users using hypothetical purchase tasks.Journal of psychopharmacology (Oxford, England) · 2020Article
- Potential for limited reinforcing and abuse-related subjective effects of intranasal oxytocin.Journal of psychopharmacology (Oxford, England) · 2020Article
- Orexin-1 Receptor Signaling in Ventral Pallidum Regulates Motivation for the Opioid Remifentanil.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Demand elasticity predicts addiction endophenotypes and the therapeutic efficacy of an orexin/hypocretin-1 receptor antagonist in rats.The European journal of neuroscience · 2019Article
- Applying behavioral economic theory to problematic Internet use: An initial investigation.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Behavioral economic purchase tasks quantify drug demand (i.e. reinforcing value of a drug) and have been used extensively to assess the value of various drugs among current users. However, purchase tasks have been rarely used with unfamiliar drugs to address a compound's abuse liability, and the current study sought to validate the paradigm in this capacity. Using a double-blind placebo-controlled within-subjects drug challenge design, the study evaluated differential drug demand on an experimental drug purchase task for a 20 mg dose of oral D-amphetamine (versus placebo), a prototypic psychostimulant, in 98 stimulant-naïve participants. Compared with placebo, amphetamine significantly increased intensity, breakpoint and O
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.