Trial reportJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research2018
Future Osteoporotic Fracture Risk Related to Lumbar Vertebral Trabecular Attenuation Measured at Routine Body CT.
Trial report in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
80 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- CT image-based biomarkers for opportunistic screening of osteoporotic fractures: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024Pooled it
- Opportunistic lumbar vertebral CT attenuation is associated with intertrochanteric femur fracture occurrence and fracture instability in older adults.Skeletal radiology · 2026Article
- VLM-Assisted Routing and HU-Traceable DICOM Adaptation for Lumbar CT HU Measurement: A Deployment-Oriented Pilot Technical Evaluation.Journal of imaging · 2026Article
- Per-Vertebra Prediction of Future Osteoporotic Fractures from Routine Computed Tomography Using a Two-Stage Machine Learning Framework.Medicina (Kaunas, Lithuania) · 2026Article
- Preoperative Computed Tomography Aortic Calcification and Attenuation of the Vertebral Body Predict Fractures Post-Kidney Transplantation Using Machine Learning.Clinical transplantation · 2026Article
- Hounsfield unit measurements from different regions of interest in lumbar spine CT: correlation with DEXA-derived bone mineral density and fracture status.BMC musculoskeletal disorders · 2026Article
- "One-stop-shop" medical imaging for osteoporosis and obese patients: a narrative review.Journal of endocrinological investigation · 2026Review
- Prediction of Osteoporosis at the Sacrum Using Opportunistic CT of the Abdomen and Pelvis: A Retrospective Feasibility Study in 277 Patients Comparing CT and QCT Data.Journal of clinical medicine · 2026Article
- Advancing osteoporosis opportunistic screening: multicenter validation of a deep learning algorithm using abdominal CT scans.Abdominal radiology (New York) · 2026Article
- Diagnostic performance of lumbar computed tomography Hounsfield unit thresholds for osteoporosis and osteopenia: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Review
- Advances in Imaging-Based Fracture Risk Assessment for Unlocking Latent Skeletal Fragility.Current osteoporosis reports · 2026Review
- Segmental distribution and influencing factors of thoracolumbar osteoporotic vertebral compression fracture.Journal of orthopaedic surgery and research · 2026Article
- Opportunistic osteoporosis screening on FDG PET/CT scans in breast carcinoma: a comparison with DXA.Asia Oceania journal of nuclear medicine & biology · 2026Article
- The Association Between Short-Term Bone Loss and Future Osteoporotic Vertebral Fractures.Clinical interventions in aging · 2026Article
- The predictive value of proximal femoral CT attenuation in intramedullary fixation failure of intertrochanteric fractures: a retrospective cohort analysis.Archives of osteoporosis · 2025Article
- CT-based hounsfield unit as an alternative osteoporosis assessment in ankylosing spondylitis patients with bamboo spine.Scientific reports · 2025Article
- Opportunistic screening for osteoporosis: validation study for L1 bone density measurements using contrast-enhanced chest and abdominal CTs.Skeletal radiology · 2025Article
- Hounsfield units predict vertebral compression fractures in gastric cancer survivors after adjuvant irradiation.Radiation oncology journal · 2025Article
- Association Between Mandibular Cortical Erosion and Bone Mineral Density Assessed by Phalangeal Ultrasound and Dual Energy X-Ray Absorptiometry in Spanish Women.Diagnostics (Basel, Switzerland) · 2025Article
20 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
We sought to determine if vertebral trabecular attenuation values measured on routine body computed tomography (CT) scans obtained for a variety of unrelated indications can predict future osteoporotic fractures at multiple skeletal sites. For this Health Insurance Portability and Accountability Act (HIPAA)-compliant and Institutional Review Board (IRB)-approved retrospective cohort study, trabecular attenuation of the first lumbar vertebra was measured in 1966 consecutive older adults who underwent chest and/or abdominal CT at a single institution over the course of 1 year. New pathologic fragility fractures that occurred after a patient's CT study date were identified through an electronic health record database query using International Classification of Diseases (ICD)-9 codes for vertebral, hip, and extremity fractures. Univariate and multivariate Cox proportional hazards regression were performed to determine the effect of L
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