ArticleThe Journal of organic chemistry2018
Organocatalytic Stereoselective Synthesis of Fluorinated 3,3'-Linked Bisoxindoles.
Article in The Journal of organic chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Enantioseparation and racemization of 3-fluorooxindoles.Chirality · 2023Article
- Selective CspSynthesis · 2022Article
- Catalytic Asymmetric Allylic Alkylation with Arylfluoroacetonitriles.The Journal of organic chemistry · 2022Article
- Catalytic stereoselective Mannich-type reactions for construction of fluorinated compounds.Molecular diversity · 2022Review
- Article
- Palladium and Nickel Catalyzed Suzuki Cross-Coupling with Alkyl Fluorides.Organic letters · 2021Article
- Catalytic Asymmetric Allylic Amination with Isatins, Sulfonamides, Imides, Amines, andOrganic letters · 2020Article
- Catalytic Enantioselective Ynamide Additions to Isatins: Concise Access to Oxindole Alkaloids.Angewandte Chemie (International ed. in English) · 2019Article
- Catalytic Asymmetric Mannich Reaction of α-Fluoronitriles with Ketimines: Enantioselective and Diastereodivergent Construction of Vicinal Tetrasubstituted Stereocenters.ACS catalysis · 2019Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
A highly diastereoselective organocatalytic method that produces 3-fluoro-3'-hydroxy-3,3'-bisoxindoles and the corresponding 3-fluoro-3'-amino derivatives having two adjacent chirality centers from fluorooxindoles and isatins in high yields is described. The reaction occurs in protic solvents at room temperature, it can be upscaled without compromising yield and stereoselectivity, and chromatographic product purification is not required.
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Registered trials
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