Evidence map›Paper›PMID 29312957›Full record

ReviewFrontiers in cardiovascular medicine2017

Patrolling Mechanics of Non-Classical Monocytes in Vascular Inflammation.

Konrad Buscher, Paola Marcovecchio, Catherine C Hedrick, Klaus Ley

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 71 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. The Modulation of Septic Shock: A Proteomic Approach.International journal of molecular sciences · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Motion Blur Microscopy.bioRxiv : the preprint server for biology · 2024
    Article
  13. Article
  14. Review
  15. Article
  16. Non-classical monocytes frequency and serum vitamin DJournal of diabetes investigation · 2023
    Article
  17. Article
  18. Article
  19. Cerebrospinal fluid CD14Journal of neurovirology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Konrad BuscherDivision of Inflammation Biology, La Jolla Institute for Allergy and Immunology, La Jolla, CA, United States.
Paola MarcovecchioDivision of Inflammation Biology, La Jolla Institute for Allergy and Immunology, La Jolla, CA, United States.
Catherine C HedrickDivision of Inflammation Biology, La Jolla Institute for Allergy and Immunology, La Jolla, CA, United States.
Klaus LeyDivision of Inflammation Biology, La Jolla Institute for Allergy and Immunology, La Jolla, CA, United States.
La Jolla Institute for Immunology · USUniversity Hospital Münster · DE

Funding

Project 4: APOB-specific CD4 and CD8 T cells exacerbate atherosclerosisP01HL136275 · NHLBI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI Catherine C Hedrick · 2017 to 2026
$25.5M
Myeloid cell interactions with T cells in atherosclerosisR01HL115232 · NHLBI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI LEY, KLAUS F. · 2012 to 2018
$3.2M
Transcriptional Control of Monocyte DevelopmentR01HL134236 · NHLBI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI HEDRICK, CATHERINE C · 2016 to 2019
$2.5M
In vivo investigation of non-classical monocyte patrolling mechanismF31HL132538 · NHLBI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI MARCOVECCHIO, PAOLA · 2016 to 2018
$98k
NHLBI NIH HHS F31 HL132538NHLBI NIH HHS P01 HL136275NHLBI NIH HHS R01 HL115232NHLBI NIH HHS R01 HL134236
6 · The paper itself

Abstract

Non-classical monocytes have emerged as the preeminent vascular housekeepers. Continuous intravascular screening is enabled by slow patrolling on the endothelium and allows a rapid response to local perturbations. Intravital imaging has been crucial to elucidate the molecular mechanisms and migratory phenotype of patrolling. In this review, we discuss technical requirements of intravital microscopy such as imaging modalities, labeling strategies, and data analysis. We further focus on patrolling kinetics and adhesion receptors in different organs and vascular beds including arteries during homeostasis and vascular inflammation and define pertinent questions in the field.

Indexed as

arteriesarteriosclerosismicrocirculationmonocytespatrollingvenules

Identifiers

PMID29312957
PMCPMC5742122
OpenAlexW2775875264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.