Evidence map›Paper›PMID 29312926›Full record

ArticleFrontiers in chemistry2017

Ethyl 3-oxo-2-(2,5-dioxopyrrolidin-3-yl)butanoate Derivatives: Anthelmintic and Cytotoxic Potentials, Antimicrobial, and Docking Studies.

Fawad Mahmood, Muhammad S Jan, Sajjad Ahmad, Umer Rashid, Muhammad Ayaz, Farhat Ullah, Fida Hussain, Ashfaq Ahmad, Arif-Ullah Khan, Muhammad Aasim and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

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  4. 3-(((1Molecules (Basel, Switzerland) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Fawad MahmoodDepartment of Pharmacy, Sarhad University of Science & Technology, Peshawar, Pakistan.
Muhammad S JanDepartment of Pharmacy, University of Malakand, Chakdara, Pakistan.
Sajjad AhmadDepartment of Pharmacy, University of Malakand, Chakdara, Pakistan.
Umer RashidDepartment of Chemistry, COMSATS Institute of Information Technology, Abbottabad, Pakistan.
Muhammad AyazDepartment of Pharmacy, University of Malakand, Chakdara, Pakistan.
Farhat UllahDepartment of Pharmacy, University of Malakand, Chakdara, Pakistan.
Fida HussainDepartment of Pharmacy, University of Malakand, Chakdara, Pakistan.
Ashfaq AhmadDepartment of Pharmacy, Sarhad University of Science & Technology, Peshawar, Pakistan.
Arif-Ullah KhanDepartment of Pharmacology, Riphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad, Pakistan.
Muhammad AasimDepartment of Biotechnology, University of Malakand, Chakdara, Pakistan.
Abdul SadiqDepartment of Pharmacy, University of Malakand, Chakdara, Pakistan.
University of Malakand · PKSarhad University of Science and Information Technology · PKCOMSATS University Islamabad · PKRiphah International University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Development of multidrug resistance (MDR) to antimicrobial, antiparasitic and chemotherapeutic agents is a global challenge for the scientific community. Despite of the emergence of MDR pathogens, the development of novel and more effective drugs is slow and scientist even speculate that we are going back the pre-antibiotic era. This work aims to study and evaluate the preliminary antibacterial, anthelmintic and cytotoxic potentials of ethyl 3-oxo-2-(2,5-dioxopyrrolidin-3-yl)butanoates. Among all of the four compounds, compound

Indexed as

anthelminiticantibacterialAscaridia gallibrine shrimpscytotoxicityMICssuccinimides

Identifiers

PMID29312926
PMCPMC5733081
OpenAlexW2773363277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.