ReviewFrontiers in cellular and infection microbiology2017
Bovine Immune Factors Underlying Tick Resistance: Integration and Future Directions.
Review in Frontiers in cellular and infection microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 52 citations in OpenAlex.
- Comprehensive evaluation of tick infestation dynamics and host response in Kankrej and Holstein Friesian crossbred cattle.Veterinary and animal science · 2026Article
- Prevalence, Species Diversity, and Risk Factors of Tick Infestation in Cattle From District Peshawar, Pakistan.Veterinary medicine and science · 2025Article
- Depicting "arms race" of Rhipicephalus microplus and its host on a single frame platform.Parasitology research · 2025Article
- Article
- Characterization and Seasonal Dynamics of Tick Populations in Dairy Cattle Production Systems of Northwestern Colombian Amazon.Veterinary sciences · 2024Article
- The potential for use of haematological and anti-IgE humoral responses as phenotypic markers for tick resistance in cattle.Current research in parasitology & vector-borne diseases · 2024Article
- More than Three Decades of Bm86: What We Know and Where to Go.Pathogens (Basel, Switzerland) · 2023Review
- Transcriptional changes in the peripheral blood leukocytes from Brangus cattle before and after tick challenge with Rhipicephalus australis.BMC genomics · 2022Article
- Proteomic profiling of plasma-derived small extracellular vesicles: a novel tool for understanding the systemic effects of tick burden in cattle.Journal of animal science · 2022Article
- Genetic Diversity and Population Structure for Resistance and Susceptibility to Mastitis in Braunvieh Cattle.Veterinary sciences · 2021Article
- From Bench to Field: A Guide to Formulating and Evaluating Anti-Tick Vaccines Delving beyond Efficacy to Effectiveness.Vaccines · 2021Review
- Monthly infestation characteristics of ticks on cattle in Thrace, a Crimean Congo hemorrhagic fever-endemic area of Turkey.Parasitology research · 2021Article
- Acquired tick resistance: The trail is hot.Parasite immunology · 2021Review
- Tick Infestation and Piroplasm Infection in Barbarine and Queue Fine de l'Ouest Autochthonous Sheep Breeds in Tunisia, North Africa.Animals : an open access journal from MDPI · 2021Article
- Improvement of Disease Resistance in Livestock: Application of Immunogenomics and CRISPR/Cas9 Technology.Animals : an open access journal from MDPI · 2020Review
- Ticks and Tick-Borne Diseases in Cuba, Half a Century of Scientific Research.Pathogens (Basel, Switzerland) · 2020Review
- Efficient Transovarial Transmission ofPathogens (Basel, Switzerland) · 2020Article
- Network analysis uncovers putative genes affecting resistance to tick infestation in Braford cattle skin.BMC genomics · 2019Article
- Metazoan Parasite Vaccines: Present Status and Future Prospects.Frontiers in cellular and infection microbiology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mechanisms underlying tick resistance within and between cattle breeds have been studied for decades. Several previous papers on bovine immune parameters contributing to tick resistance discussed findings across DNA, RNA, protein, cellular, and tissue levels. However, the differences between bovine host species, tick species and the experimental layouts were not always taken into account. This review aims to (a) give a comprehensive summary of studies investigating immune marker differences between cattle breeds with varying degrees of tick resistance, and (b) to integrate key findings and suggest hypotheses on likely immune-regulated pathways driving resistance. Experimental issues, which may have skewed conclusions, are highlighted. In future, improved experimental strategies will enable more focused studies to identify and integrate immune markers and/or pathways. Most conclusive thus far is the involvement of histamine, granulocytes and their associated pathways in the tick-resistance mechanism. Interestingly, different immune markers might be involved in the mechanisms within a single host breed in contrast to between breeds. Also, differences are evident at each tick life stage, limiting the level to which datasets can be compared. Future studies to further elucidate immune molecule dynamics across the entire tick life cycle and in-depth investigation of promising markers and pathways on both molecular and cellular level are in dire need to obtain a scientifically sound hypothesis on the drivers of tick resistance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.