Evidence map›Paper›PMID 29312895›Full record

ArticleFrontiers in cellular and infection microbiology2017

Tick-Host Range Adaptation: Changes in Protein Profiles in Unfed Adult

Lucas Tirloni, Tae K Kim, Antônio F M Pinto, John R Yates, Itabajara da Silva Vaz, Albert Mulenga

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 87 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Multidimensional mechanisms of SFTSV-host interactions: viral protein functions, mFrontiers in cellular and infection microbiology · 2026
    Review
  5. Acquired tick resistance inInfection and immunity · 2025
    Article
  6. Article
  7. Article
  8. Anti-IL-4, Anti-IL-17, and Anti-IFN-Gamma Activity in the Saliva ofInternational journal of molecular sciences · 2025
    Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Universal Tick Vaccines: Candidates and Remaining Challenges.Animals : an open access journal from MDPI · 2023
    Review
  17. Article
  18. Frontiers in cellular and infection microbiology · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Lucas TirloniDepartment of Veterinary Pathobiology, College of Veterinary Medicine, Texas A&M University, College Station, TX, United States.
Tae K KimDepartment of Veterinary Pathobiology, College of Veterinary Medicine, Texas A&M University, College Station, TX, United States.
Antônio F M PintoMass Spectrometry Center, The Salk Institute for Biological Studies, La Jolla, CA, United States.
John R YatesDepartment of Chemical Physiology, The Scripps Research Institute, La Jolla, CA, United States.
Itabajara da Silva VazCentro de Biotecnologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Albert MulengaDepartment of Veterinary Pathobiology, College of Veterinary Medicine, Texas A&M University, College Station, TX, United States.
Texas A&M University · USScripps Research Institute · USUniversidade Federal do Rio Grande do Sul · BR

Funding

TrainingP41GM103533 · NIGMS · UNIVERSITY OF WASHINGTON · PI MACCOSS, MICHAEL · 2012 to 2021
$20.7M
Tick feeding regulation by orthologous tick saliva serine protease inhibitorsR01AI093858 · NIAID · TEXAS A&M UNIVERSITY · PI MULENGA, ALBERT · 2011 to 2014
$1.0M
Molecular Mechanisms Regulating Early Stage Tick FeedingR21AI081093 · NIAID · TEXAS A&M UNIVERSITY · PI MULENGA, ALBERT · 2011 to 2012
$404k
Serine Proteinase Inhibitors (Serpins) in Tick Feeding and PhysiologyR03AI074789 · NIAID · TEXAS A&M UNIVERSITY · PI MULENGA, ALBERT · 2008 to 2009
$229k
NIAID NIH HHS R01 AI093858NIAID NIH HHS R03 AI074789NIAID NIH HHS R21 AI081093NIGMS NIH HHS P41 GM103533
6 · The paper itself

Abstract

Understanding the molecular basis of how ticks adapt to feed on different animal hosts is central to understanding tick and tick-borne disease (TBD) epidemiology. There is evidence that ticks differentially express specific sets of genes when stimulated to start feeding. This study was initiated to investigate if ticks such as

Indexed as

Host SpecificityAnimalsArthropod ProteinsChromatography, LiquidDogsElectrophoresis, Polyacrylamide GelHumansIxodidaeProteomeRabbitsSalivaSalivary Proteins and PeptidesTandem Mass SpectrometryArthropod ProteinsProteomeSalivary Proteins and Peptideshost adaptationproteomicsalivaticktick-host relationship

Identifiers

PMID29312895
PMCPMC5742094
OpenAlexW2780910568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.