Evidence map›Paper›PMID 29312882›Full record

ReviewFrontiers in oncology2017

Future Directions of Intraoperative Radiation Therapy: A Brief Review.

Tatjana Paunesku, Gayle E Woloschak

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
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  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. [Intraoperative radiotherapy in abdominal surgery-Own experiences].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2020
    Article
  12. [Intraoperative radiotherapy-Indications and options in visceral surgery].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2020
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Tatjana PauneskuDepartment of Radiation Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Gayle E WoloschakDepartment of Radiation Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Northwestern University · US

Funding

Radiation induced cancer risk reduction as a function of dose protraction: interspecies comparisonR01CA221150 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI WOLOSCHAK, GAYLE E. · 2017 to 2021
$1.7M
NCI NIH HHS R01 CA221150
6 · The paper itself

Abstract

The use of intraoperative radiation therapy (IORT) is increasing with the development of new devices for patient treatment that allow irradiation without the need to move the patient from the surgical table. At the moment, ionizing radiation in the course of IORT is supported most often by the use of mobile devices that produce electrons, kilo voltage X-rays, and electronic brachytherapy and the development of applicators suitable for delivery of radionuclides for short-term brachytherapy. The establishment of new treatment devices and protocols that can be foreseen in the future, e.g., the development of proton or heavy ion sources suitable for IORT or the establishment of new treatment protocols such as the use of IORT in combination with immune system modulators or radiosensitizing nanoparticles, could lead to a significant increase in the use of IORT in the future. This review discusses the still limited use of IORT at this point in time and hypothesizes about possible future approaches to radiotherapy.

Indexed as

immunotherapyintraoperative radiation therapynanotechnologynormal tissue injuryradiosensitizers

Identifiers

PMID29312882
PMCPMC5732937
OpenAlexW2774135094

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.