Evidence map›Paper›PMID 29312806›Full record

ArticleAmerican journal of cancer research2017

Long non-coding RNA LINC00673 promotes hepatocellular carcinoma progression and metastasis through negatively regulating miR-205.

Li-Guo Zhang, Xin-Ke Zhou, Ru-Jian Zhou, Hui-Zeng Lv, Wei-Peng Li

Open access · greenAbstract read
In one paragraph

Article in American journal of cancer research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Genetic Polymorphisms of lncRNAInternational journal of molecular sciences · 2022
    Article
  5. Review
  6. NF-Journal of oncology · 2022
    Article
  7. A review of linc00673 as a novel lncRNA for tumor regulation.International journal of medical sciences · 2021
    Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Frontiers in genetics · 2019
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Li-Guo ZhangDepartment of General Surgery, Fifth Affiliated Hospital of Guangzhou Medical UniversityNo. 621, Harbor Road, Huangpu District, Guangzhou 510000, China.
Xin-Ke ZhouDepartment of General Surgery, Fifth Affiliated Hospital of Guangzhou Medical UniversityNo. 621, Harbor Road, Huangpu District, Guangzhou 510000, China.
Ru-Jian ZhouDepartment of General Surgery, Fifth Affiliated Hospital of Guangzhou Medical UniversityNo. 621, Harbor Road, Huangpu District, Guangzhou 510000, China.
Hui-Zeng LvDepartment of General Surgery, Fifth Affiliated Hospital of Guangzhou Medical UniversityNo. 621, Harbor Road, Huangpu District, Guangzhou 510000, China.
Wei-Peng LiDepartment of General Surgery, Fifth Affiliated Hospital of Guangzhou Medical UniversityNo. 621, Harbor Road, Huangpu District, Guangzhou 510000, China.
Guangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increasing evidence demonstrates abnormal expression of long non-coding RNA (lncRNA) is closely correlated with various malignancies including hepatocellular carcinoma (HCC). The present study aims to investigate the role of lncRNA long intergenic noncoding RNA 00673 (LINC00673) in tumorigenesis of HCC. Quantitative real-time polymerase chain reaction (qRT-PCR) revealed LINC00673 was upregulated in HCC cancerous tissue and cell lines compared to adjacent normal tissue and normal liver cell lines. LINC00673 overexpression is associated with poor prognosis and low survival rate. LINC00673 silencing inhibited the proliferation, invasion and epithelial-mesenchymal transition (EMT) of HCC cells in

Indexed as

EMTHepatocellular carcinomaLINC00673lncRNAmetastasismiR-205

Identifiers

PMID29312806
PMCPMC5752693
OpenAlexW2976151714

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.