Evidence map›Paper›PMID 29312556›Full record

ArticleOncotarget2017

Improving anti-melanoma effect of curcumin by biodegradable nanoparticles.

Bilan Wang, Xiaoxiao Liu, Yan Teng, Ting Yu, Junli Chen, Yuzhu Hu, Na Liu, Lingli Zhang, Yangmei Shen

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Bilan WangDepartment of Pharmacy, West China Second university Hospital, Sichuan University, Chengdu, PR China.
Xiaoxiao LiuDepartment of Radiation Oncolo, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.
Yan TengResearch Unit of Infection and Immunity, Department of Pathophysiology, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, Sichuan, China.
Ting YuCancer Center, West China Hospital, West China Medical School, Sichuan University and Collaborative Innovation Center, Chengdu, PR China.
Junli ChenResearch Unit of Infection and Immunity, Department of Pathophysiology, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, Sichuan, China.
Yuzhu HuCancer Center, West China Hospital, West China Medical School, Sichuan University and Collaborative Innovation Center, Chengdu, PR China.
Na LiuResearch Unit of Infection and Immunity, Department of Pathophysiology, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, Sichuan, China.
Lingli ZhangDepartment of Pharmacy, West China Second university Hospital, Sichuan University, Chengdu, PR China.
Yangmei ShenDepartment of Pathology, West China Second university Hospital, Sichuan University, Chengdu, PR China.
West China Medical Center of Sichuan University · CNSichuan University · CNNanyang Medical College · CNXuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melanoma is known as the most common malignant cutaneous cancer. Curcumin, a natural component, has been shown to have various activities such as anti-oxidant, anti-septic, anti-inflammatory, anti-biotic, anti-amyloid and anti-thrombosis. However, there is a greatest obstacle in the administration of curcumin due to its hydrophobicity and low oral bioavailability. In this study, we formulated curcumin-loaded MPEG-PLA (Curcumin/MPEG-PLA) micelles aiming to improve its solubility in aqueous solution and investigated anti-tumor effect on melanoma

Indexed as

cell apoptosiscurcuminmelanomamicelles

Identifiers

PMID29312556
PMCPMC5752469
OpenAlexW2752944194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.