ArticleAmerican journal of translational research2017
High-intensity resistance training alone or combined with aerobic training improves strength, heart function and collagen in rats with heart failure.
Article in American journal of translational research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 15 citations in OpenAlex.
- Strength training improves heart function, collagen and strength in rats with heart failure.The journal of physiological sciences : JPS · 2024Article
- Influence of Isolated Resistance Exercise on Cardiac Remodeling, Myocardial Oxidative Stress, and Metabolism in Infarcted Rats.Antioxidants (Basel, Switzerland) · 2023Article
- Heart Failure with Preserved Ejection Fraction: Pathogenesis, Diagnosis, Exercise, and Medical Therapies.Journal of cardiovascular translational research · 2023Review
- EFFECT OF AEROBIC AND ANAEROBIC TRAINING ON DIFFERENT ERGOMETERS IN RAT MUSCLE AND HEART TISSUES.Acta ortopedica brasileira · 2022Article
- A Systematic Review and Meta-Analysis of the Effectiveness of High-Intensity Interval Training in People with Cardiovascular Disease at Improving Depression and Anxiety.Evidence-based complementary and alternative medicine : eCAM · 2022Review
- Unveiling the role of exercise training in targeting the inflammatory paradigm of heart failure with preserved ejection fraction: a narrative review.Heart failure reviews · 2022Review
- Impacts of exercise intervention on various diseases in rats.Journal of sport and health science · 2020Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundResistance training (RT) has been associated with positive responses in patients with cardiovascular disease, and when it is combined with continuous aerobic training (CAT), favorable adaptations appear to be even more pronounced. However, the effects of high-intensity RT alone or in combined with CAT in the case of heart failure (HF) is not completely elucidated.
methods28 male Wistar rats with HF (90 days old) were allocated to 4 groups: high-intensity RT (RT, n=7), CAT (CAT, n=7), RT and CAT (RT+CAT, n=7) and sedentary (Sed, n=7). Trained animals were subjected to a RT protocol in an adapted squat apparatus for rats (4 bouts, 6-8 reps, 90 s interval, 3×/week, 75% to 85% of one maximum repetition (1RM) for 8 weeks). The animals subjected to CAT performed it 3×/week during 50 min/session at 16 m/min. The animals of the combined exercise regimen performed both the RT and CAT exercise protocols.
resultsThe left ventricular end-diastolic pressure (LVEDP), collagen volume fraction and right ventricular hypertrophy were lower in RT, CAT and RT+CAT groups when compared to Sed group (P<0.05) for all outcomes. Regarding the inflammatory profile, only the CAT group showed greater IL-10 concentrations.
conclusionWe concluded that RT combined with CAT was able to improve the strength in animals with HF, which was associated to improvement in ventricular structure and function.
Indexed as
Identifiers
29312495PMC5752893W2975915784What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.