Evidence map›Paper›PMID 29312477›Full record

ReviewAmerican journal of translational research2017

Multifunctionalization of graphene and graphene oxide for controlled release and targeted delivery of anticancer drugs.

Cui-Cui Liu, Jing-Jing Zhao, Rui Zhang, Hui Li, Bo Chen, Ling-Ling Zhang, Hao Yang

Abstract readReview
In one paragraph

Review in American journal of translational research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Synthesis of Graphene Oxide-FeInternational journal of molecular sciences · 2019
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cui-Cui LiuTranslational Medicine Center, Hong-Hui Hospital, Xi'an Jiaotong University College of MedicineXi'an 710054, China.
Jing-Jing ZhaoTranslational Medicine Center, Hong-Hui Hospital, Xi'an Jiaotong University College of MedicineXi'an 710054, China.
Rui ZhangTranslational Medicine Center, Hong-Hui Hospital, Xi'an Jiaotong University College of MedicineXi'an 710054, China.
Hui LiJoint Surgery, Hong-Hui Hospital, Xi'an Jiaotong University College of MedicineXi'an 710054, China.
Bo ChenTranslational Medicine Center, Hong-Hui Hospital, Xi'an Jiaotong University College of MedicineXi'an 710054, China.
Ling-Ling ZhangTranslational Medicine Center, Hong-Hui Hospital, Xi'an Jiaotong University College of MedicineXi'an 710054, China.
Hao YangTranslational Medicine Center, Hong-Hui Hospital, Xi'an Jiaotong University College of MedicineXi'an 710054, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among various nanomaterials, graphene and its derivatives have attracted considerable research interest in diverse application areas-including nanomedicine-because of their extraordinary physical, chemical, and optical properties. Intensive research is underway to investigate the biomedical application of graphene and graphene-based nanosystems as drug-delivery vehicles for cancer therapy, and this is considered as one of the novel therapeutic approaches for performing on-demand chemotherapy coupled with photothermal therapy or photodynamic therapy. Here, we systematically summarize recent progress in the synthesis and functionalization of graphene by using a vast range of materials, including small molecules, polymers, and biomolecules, in order to overcome the inherent drawbacks of graphene oxide (GO) nanocarriers and thereby make these nanocarriers suitable for delivering chemotherapeutic agents, genes, and short interfering RNAs. Moreover, we address the opportunities and challenges associated with future clinical application of GO for cancer therapy.

Indexed as

cancer therapydrug-delivery systemfunctionalizationGraphenegraphene oxidenanomedicine

Identifiers

PMID29312477
PMCPMC5752875

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.