Evidence map›Paper›PMID 29312357›Full record

ReviewFrontiers in immunology2017

Antigen Presentation by Vascular Cells.

Jordan S Pober, Jonathan Merola, Rebecca Liu, Thomas D Manes

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 112 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
112citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

112 citing papers in PubMed, 1 synthesis or guideline pooled it, 156 citations in OpenAlex.

  1. Myocardial Immune Cells: The Basis of Cardiac Immunology.Journal of immunology (Baltimore, Md. : 1950) · 2023
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Endothelial Elavl1 Is Required for CD8 T-Cell Persistence in Atherosclerosis.Arteriosclerosis, thrombosis, and vascular biology · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Frontiers in cellular and infection microbiology · 2026
    Article
  11. Review
  12. Article
  13. Endothelial cells as targets of immune checkpoint blockade.Journal for immunotherapy of cancer · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Best practices of heart transplantation in mice.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025
    Review
  18. Article
  19. Article
  20. Regulatory T cell and endothelial cell crosstalk.Nature reviews. Immunology · 2025
    Review

52 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jordan S PoberDepartment of Immunobiology, Yale School of Medicine, New Haven, CT, United States.
Jonathan MerolaDepartment of Surgery, Yale School of Medicine, New Haven, CT, United States.
Rebecca LiuDepartment of Immunobiology, Yale School of Medicine, New Haven, CT, United States.
Thomas D ManesDepartment of Immunobiology, Yale School of Medicine, New Haven, CT, United States.
Yale University · US

Funding

Presentation of Alloantigen by Human Vascular CellsR01HL051014 · NHLBI · YALE UNIVERSITY · PI MANES, THOMAS DAVID, POBER, JORDAN S · 1994 to 2019
$10.4M
PATHOPHYSIOLOGY OF ACUTE AND CHRONIC RENAL DISEASET32DK007276 · NIDDK · YALE UNIVERSITY · PI ARONSON, PETER S., CANTLEY, LLOYD G · 1986 to 2022
$9.3M
Modulation of Inflammation and Injury by IL-17-Activated PericytesF31HL129563 · NHLBI · YALE UNIVERSITY · PI LIU, REBECCA · 2015 to 2016
$56k
NHLBI NIH HHS F31 HL129563NHLBI NIH HHS R01 HL051014NIDDK NIH HHS T32 DK007276
6 · The paper itself

Abstract

Antigen presentation by cells of the vessel wall may initiate rapid and localized memory immune responses in peripheral tissues. Peptide antigens displayed on major histocompatibility complex (MHC) molecules on the surface of endothelial cells (ECs) can be recognized by T cell receptors on circulating effector memory T cells (T

Indexed as

effector memory T cellsendothelial cellspericytesregulatory T cellssmooth muscle cellstransendothelial migration

Identifiers

PMID29312357
PMCPMC5744398
OpenAlexW2780075441

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.