Evidence map›Paper›PMID 29312340›Full record

ArticleFrontiers in immunology2017

Public Clonotypes and Convergent Recombination Characterize the Naïve CD8

Alison J Carey, Jennifer L Hope, Yvonne M Mueller, Adam J Fike, Ogan K Kumova, David B H van Zessen, Eric A P Steegers, Mirjam van der Burg, Peter D Katsikis

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 34 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Perturbation of the Preterm Human Immune System in Early Life.medRxiv : the preprint server for health sciences · 2025
    Article
  8. Review
  9. Article
  10. Review
  11. Granzyme KNature communications · 2024
    Article
  12. Article
  13. Clonally expanded memory CD8Nature aging · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Alison J CareyDepartment of Pediatrics, Drexel University College of Medicine, Philadelphia, PA, United States.
Jennifer L HopeDepartment of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA, United States.
Yvonne M MuellerDepartment of Immunology, Erasmus University Medical Center, Rotterdam, Netherlands.
Adam J FikeDepartment of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA, United States.
Ogan K KumovaDepartment of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA, United States.
David B H van ZessenDepartment of Immunology, Erasmus University Medical Center, Rotterdam, Netherlands.
Eric A P SteegersDepartment of Obstetrics and Gynecology, Erasmus University Medical Center, Rotterdam, Netherlands.
Mirjam van der BurgDepartment of Immunology, Erasmus University Medical Center, Rotterdam, Netherlands.
Peter D KatsikisDepartment of Immunology, Erasmus University Medical Center, Rotterdam, Netherlands.
Erasmus MC · NLDrexel University · US

Funding

Investigation of Neonatal Influenza PathogenesisK08AI108791 · NIAID · DREXEL UNIVERSITY · PI CAREY, ALISON J · 2014 to 2018
$886k
NIAID NIH HHS K08 AI108791
6 · The paper itself

Abstract

Respiratory support improvements have aided survival of premature neonates, but infection susceptibility remains a predominant problem. We previously reported that neonatal mice have a rapidly evolving T-cell receptor (TCR) repertoire that impairs CD8

Indexed as

convergent recombinationdiversity analysisneonatepretermpublic clonotypesT-cell receptor repertoire

Identifiers

PMID29312340
PMCPMC5742125
OpenAlexW2779924612

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.