Evidence map›Paper›PMID 29312311›Full record

ArticleFrontiers in immunology2017

Partial CD25 Antagonism Enables Dominance of Antigen-Inducible CD25

Daniel S Wilkinson, Debjani Ghosh, Rebecca A Nickle, Cody D Moorman, Mark D Mannie

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Therapeutic Effect of IL-21 Blockage by Gene Therapy in Experimental Autoimmune Encephalomyelitis.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Daniel S WilkinsonDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC, United States.
Debjani GhoshDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC, United States.
Rebecca A NickleDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC, United States.
Cody D MoormanDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC, United States.
Mark D MannieDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC, United States.
East Carolina University · US

Funding

Interferon-beta as an Adjuvant for Tolerogenic VaccinationR01AI126398 · NIAID · EAST CAROLINA UNIVERSITY · PI MANNIE, MARK D. · 2016 to 2020
$2.1M
Interferons as adjuvants for tolerogenic vaccinesR01NS072150 · NINDS · EAST CAROLINA UNIVERSITY · PI MANNIE, MARK D. · 2011 to 2015
$1.5M
Therapeutic vaccines for treatment of experimental autoimmune encephalomyelitis (R15NS075830 · NINDS · EAST CAROLINA UNIVERSITY · PI MANNIE, MARK D. · 2011 to 2011
$429k
NIAID NIH HHS R01 AI126398NINDS NIH HHS R01 NS072150NINDS NIH HHS R15 NS075830
6 · The paper itself

Abstract

FOXP3

Indexed as

experimental autoimmune encephalomyelitis/MSFOXP3neuroimmunologyregulatory T cellsrodenttolerance

Identifiers

PMID29312311
PMCPMC5735073
OpenAlexW2772231333

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.