Evidence map›Paper›PMID 29312289›Full record

ArticleFrontiers in immunology2017

Immune Checkpoints in Leprosy: Immunotherapy As a Feasible Approach to Control Disease Progression.

Hayana Ramos Lima, Thaís Helena Gasparoto, Tatiana Salles de Souza Malaspina, Vinícius Rizzo Marques, Marina Jurado Vicente, Elaine Camarinha Marcos, Fabiana Corvolo Souza, Maria Renata Sales Nogueira, Jaison Antônio Barreto, Gustavo Pompermaier Garlet and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Expression of annexin-A1 in blood and tissue leukocytes of leprosy patients.Revista da Sociedade Brasileira de Medicina Tropical · 2020
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Hayana Ramos LimaDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil.
Thaís Helena GasparotoDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil.
Tatiana Salles de Souza MalaspinaDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil.
Vinícius Rizzo MarquesDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil.
Marina Jurado VicenteDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil.
Elaine Camarinha MarcosLauro de Souza Lima Institute, Bauru, Brazil.
Fabiana Corvolo SouzaLauro de Souza Lima Institute, Bauru, Brazil.
Maria Renata Sales NogueiraLauro de Souza Lima Institute, Bauru, Brazil.
Jaison Antônio BarretoLauro de Souza Lima Institute, Bauru, Brazil.
Gustavo Pompermaier GarletDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil.
João Santana da SilvaDepartment of Biochemistry and Immunology, School of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.
Vânia Nieto Brito-de-SouzaLauro de Souza Lima Institute, Bauru, Brazil.
Ana Paula CampanelliDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil.
Universidade de São Paulo · BRInstituto Lauro de Souza Lima · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leprosy remains a health problem in several countries. Current management of patients with leprosy is complex and requires multidrug therapy. Nonetheless, antibiotic treatment is insufficient to prevent nerve disabilities and control

Indexed as

cytotoxic T-lymphocyte-associated protein 4immune checkpoint blockadeimmunotherapyleprosyPD-1:PD-L1T-regulatory cells

Identifiers

PMID29312289
PMCPMC5732247
OpenAlexW2772766700

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.