Evidence map›Paper›PMID 29312280›Full record

ArticleFrontiers in immunology2017

Effects of Soluble Corn Fiber Alone or in Synbiotic Combination with

Adele Costabile, Triana Bergillos-Meca, Pia Rasinkangas, Katri Korpela, Willem M de Vos, Glenn R Gibson

3 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 42 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 5 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07439978 phase1not yet recruitingnot on this mapstarted 2026, after this paper: background citation

A Physiological Study of a Fermented Yogurt Drink Containing Probiotics

TypeinterventionalSponsorUniversity College DublinRan2026 to 2026Enrolled50ConditionsColonization, Asymptomatic, ColonisationArmsprobiotic containing L.rhamnosus R0011 strain, 200 ml yogurt drink
NCT07510282 phase1not yet recruitingnot on this mapstarted 2026, after this paper: background citation

A Physiological Study on How Probiotic Delivered to the Small Intestine Changes Microbiota

TypeinterventionalSponsorUniversity College DublinRan2026 to 2026Enrolled25ConditionsColonization, Asymptomatic, ColonizationArmsProbiotic containing L.rhamnosus R0011 strain, 200 ml yogurt drink
NCT07679490 naactive not recruitingnot on this mapstarted 2026, after this paper: background citation

A Physiological Study of a Fruit Snack Containing Probiotics

TypeinterventionalSponsorUniversity College DublinRan2026 to 2027Enrolled25ConditionsColonization, Asymptomatic, Probiotic Intervention, Gut Microbiota Diversity and Composition, Gut-brain AxisArmsMicroencapsulated Lactobacillus rhamnosus Fruit Snack, Placebo Fruit Snack
3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 5 syntheses or guidelines pooled it, 89 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Trial
  8. ProbioticNutrients · 2022
    Trial
  9. Trial
  10. Trial
  11. Article
  12. Review
  13. Life (Basel, Switzerland) · 2025
    Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Influence ofFoods (Basel, Switzerland) · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Adele CostabileHealth Sciences Research Centre, Life Sciences Department, Whitelands College, University of Roehampton, London, United Kingdom.
Triana Bergillos-MecaHealth Sciences Research Centre, Life Sciences Department, Whitelands College, University of Roehampton, London, United Kingdom.
Pia RasinkangasDepartment of Veterinary Biosciences, University of Helsinki, Helsinki, Finland.
Katri KorpelaImmunobiology Research Program, Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland.
Willem M de VosDepartment of Veterinary Biosciences, University of Helsinki, Helsinki, Finland.
Glenn R GibsonDepartment of Food and Nutritional Sciences, University of Reading, Reading, United Kingdom.
University of Helsinki · FIUniversity of Reading · GBUniversity of Roehampton · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aging process leads to a potential decline in immune function and adversely affects the gut microbiota. To date, many

objectivesWe investigated the effects of a probiotic

resultsConsumption of

conclusionIn conclusion, the synbiotic combination of

Indexed as

fecal microbiotaimmunityLactobacillus rhamnosus GGLactobacillus rhamnosus GG-PB12metabolismpilus-deficientSoluble Corn Fiber

Identifiers

PMID29312280
PMCPMC5733116
OpenAlexW2781690695

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.