Evidence map›Paper›PMID 29312152›Full record

ArticleFrontiers in endocrinology2017

Aerobic Training Improves Angiogenic Potential Independently of Vascular Endothelial Growth Factor Modifications in Postmenopausal Women.

Pascal Izzicupo, Maria A D'Amico, Andrea Di Blasio, Giorgio Napolitano, Fabio Y Nakamura, Angela Di Baldassarre, Barbara Ghinassi

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Inflammaging and Cardiovascular Risk in Old Women.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Effect of Adherence to Physical Exercise on Cardiometabolic Profile in Postmenopausal Women.International journal of environmental research and public health · 2021
    Article
  14. Article
  15. The Length and Number of Sedentary Bouts Predict Fibrinogen Levels in Postmenopausal Women.International journal of environmental research and public health · 2020
    Article
  16. Review
  17. Gender-Specific Differences in Concentrations of Biochemical Parameters in Persons over the Age of 90.International journal of environmental research and public health · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pascal IzzicupoDepartment of Medicine and Aging Science, University "G. d'Annunzio" of Chieti - Pescara, Chieti, Italy.
Maria A D'AmicoDepartment of Medicine and Aging Science, University "G. d'Annunzio" of Chieti - Pescara, Chieti, Italy.
Andrea Di BlasioDepartment of Medicine and Aging Science, University "G. d'Annunzio" of Chieti - Pescara, Chieti, Italy.
Giorgio NapolitanoDepartment of Medicine and Aging Science, University "G. d'Annunzio" of Chieti - Pescara, Chieti, Italy.
Fabio Y NakamuraDepartment of Medicine and Aging Science, University "G. d'Annunzio" of Chieti - Pescara, Chieti, Italy.
Angela Di BaldassarreDepartment of Medicine and Aging Science, University "G. d'Annunzio" of Chieti - Pescara, Chieti, Italy.
Barbara GhinassiDepartment of Medicine and Aging Science, University "G. d'Annunzio" of Chieti - Pescara, Chieti, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study is to evaluate the effect of walking-training on the balance between pro- and antiangiogenic signals and on the angiogenic potential in postmenopausal women. MATERIALS AND

methodsThirty-four postmenopausal women (56.18 ± 4.24 years) participated in a 13 weeks program of walking-training. Anthropometric measures, vascular endothelial growth factor (VEGF), interleukin (IL)-1α, IL-1β, IL-2, IL-8, IL-10, IL-12p70, tumor necrosis factor-α (TNF-α), C-reactive protein, insulin, IGF-1, cortisol, dehydroepiandrosterone sulfate (DHEA-S), leptin, visfatin, resistin, and adiponectin were evaluated before and after training. Moreover, serum samples were tested for their ability to chemo-attract endothelial cells and to support the

resultsAfter training, the levels of IL-8, TNF-α, leptin, and resistin were significantly lower, levels of DHEA-S and adiponectin increased, serum angiogenic properties improved, whereas no changes in anthropometric parameters or VEGF were detected.

conclusionWalking training reduces inflammatory status and leads to a significant improvement in serum angiogenic properties in the absence of modifications in body composition and VEGF level.

Indexed as

adipokinesangiogenesisexerciseinflammationmenopausevascular endothelial growth factor

Identifiers

PMID29312152
PMCPMC5742914

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.