Evidence map›Paper›PMID 29311898›Full record

ArticleFrontiers in aging neuroscience2017

The

Chris J Carter, James France, StJohn Crean, Sim K Singhrao

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07233512 (EFFECT OF SURGICAL AND NON-SURGICAL PERIODONTAL TREATMENT ON ALZHEIMER DISEASE-ASSOCIATED OUTCOMES), which is not on this map. Cited by 62 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 3 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07233512 naenrolling by invitationnot on this mapstarted 2023, after this paper: background citation

EFFECT OF SURGICAL AND NON-SURGICAL PERIODONTAL TREATMENT ON ALZHEIMER DISEASE-ASSOCIATED OUTCOMES: A Randomized Clinical Trial

TypeinterventionalSponsorCentre Hospitalier Universitaire de LiegeRan2023 to 2029Enrolled26ConditionsAlzheimers Disease, PeriodontitisArmsINITIAL PERIODONTAL THERAPY
3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 3 syntheses or guidelines pooled it, 94 citations in OpenAlex.

  1. Pooled it
  2. Analysis the Link between Periodontal Diseases and Alzheimer's Disease: A Systematic Review.International journal of environmental research and public health · 2021
    Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. The relationship betweenJournal of Alzheimer's disease : JAD · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Exploring the Genetic and Functional Diversity ofInternational journal of molecular sciences · 2025
    Article
  13. Review
  14. Frontiers in immunology · 2025
    Review
  15. Association BetweenInfection and drug resistance · 2025
    Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Chris J CarterPolygenic Pathways, Hastings, United Kingdom.
James FranceDementia and Neurodegenerative Diseases Research Group, Faculty of Clinical and Biomedical Sciences, School of Dentistry, University of Central Lancashire, Preston, United Kingdom.
StJohn CreanDementia and Neurodegenerative Diseases Research Group, Faculty of Clinical and Biomedical Sciences, School of Dentistry, University of Central Lancashire, Preston, United Kingdom.
Sim K SinghraoDementia and Neurodegenerative Diseases Research Group, Faculty of Clinical and Biomedical Sciences, School of Dentistry, University of Central Lancashire, Preston, United Kingdom.
University of Central Lancashire · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontal disease is of established etiology in which polymicrobial synergistic ecology has become dysbiotic under the influence of

Indexed as

Alzheimer's diseasecardiovasculardiabetesinteractomePorphyromonas gingivalis

Identifiers

PMID29311898
PMCPMC5732932
OpenAlexW2775078795

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.