Evidence map›Paper›PMID 29311806›Full record

ArticleFrontiers in molecular neuroscience2017

Regulation of cAMP Responsive Element Binding Protein 3-Like 1 (Creb3l1) Expression by Orphan Nuclear Receptor Nr4a1.

Michael P Greenwood, Mingkwan Greenwood, Benjamin T Gillard, R Chitra Devi, David Murphy

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Michael P GreenwoodSchool of Clinical Sciences, University of Bristol, Bristol, United Kingdom.
Mingkwan GreenwoodSchool of Clinical Sciences, University of Bristol, Bristol, United Kingdom.
Benjamin T GillardSchool of Clinical Sciences, University of Bristol, Bristol, United Kingdom.
R Chitra DeviDepartment of Physiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
David MurphySchool of Clinical Sciences, University of Bristol, Bristol, United Kingdom.
University of Malaya · MYUniversity of Bristol · GB

Funding

Biotechnology and Biological Sciences Research Council BB/G006156/1Biotechnology and Biological Sciences Research Council BB/J015415/1Medical Research Council MR/N022807/1
6 · The paper itself

Abstract

Cyclic AMP (cAMP) inducible transcription factor cAMP responsive element binding protein 3 like 1 (Creb3l1) is strongly activated in the hypothalamus in response to hyperosmotic cues such as dehydration (DH). We have recently shown that Creb3l1 expression is upregulated by cAMP pathways

Indexed as

cAMPhypothalamusmethylationtranscriptional activationtranscription factorsvasopressin

Identifiers

PMID29311806
PMCPMC5732970
OpenAlexW2773601800

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.