Evidence map›Paper›PMID 29311747›Full record

ReviewNature neuroscience2018

Studying and modifying brain function with non-invasive brain stimulation.

Rafael Polanía, Michael A Nitsche, Christian C Ruff

3 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 489 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
489citing papers in PubMed, 15 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03805854 nacompletednot on this mapstarted 2019, after this paper: background citation

Modulating Pain Using Transcranial Alternating Stimulation (tACS) in Healthy Human Subjects

TypeinterventionalSponsorTechnical University of MunichRan2019 to 2019Enrolled39ConditionsExperimental Pain in Healthy Human SubjectsArms10 Hz tACS of the bilateral somatosensory cortex, 10 Hz tACS of the prefrontal cortex, 80 Hz tACS of the bilateral somatosensory cortex, 80 Hz tACS of the prefrontal cortex, Sham stimulation of the bilateral somatosensory cortex
NCT04291573 nacompletednot on this mapstarted 2021, after this paper: background citation

Recovering Arm Function in Chronic Post-stroke Patients Using Combined HD-tDCS and Virtual Reality Therapy

TypeinterventionalSponsorUniversity Hospital, MontpellierRan2021 to 2025Enrolled58ConditionsChronic Post Stroke IndividualsArmsHD-tDCS, Sham HD-tDCS
NCT06775145 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Therapeutic Effect of Neuromodulation on Anxiety Disorders by High-Definition Transcranial Electrical Stimulation

TypeinterventionalSponsorNational Taiwan University HospitalRan2025 to 2025Enrolled100ConditionsGeneralized Anxiety Disorder (GAD)ArmsHD-R_cDC+cTBS & sham-L_aDC+iTBS, sham-R_cDC+cTBS & HD-L_aDC+iTBS, HD-R_cDC+cTBS & HD-L_aDC+iTBS, sham-R_cDC+cTBS & sham-L_aDC+iTBS
3 · Its place in the literature

Who cites it

489 citing papers in PubMed, 15 syntheses or guidelines pooled it.

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429 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rafael PolaníaLaboratory for Social and Neural Systems Research (SNS-Lab), Department of Economics, University of Zurich, Zurich, Switzerland. rafael.polania@econ.uzh.ch.ORCID 0000-0002-6176-6806
Michael A NitscheLeibniz Research Center for Working Environment and Human Factors, Department of Psychology and Neurosciences, TU Dortmund, Dortmund, Germany.
Christian C RuffLaboratory for Social and Neural Systems Research (SNS-Lab), Department of Economics, University of Zurich, Zurich, Switzerland. christian.ruff@econ.uzh.ch.ORCID 0000-0002-3964-2364

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the past three decades, our understanding of brain-behavior relationships has been significantly shaped by research using non-invasive brain stimulation (NIBS) techniques. These methods allow non-invasive and safe modulation of neural processes in the healthy brain, enabling researchers to directly study how experimentally altered neural activity causally affects behavior. This unique property of NIBS methods has, on the one hand, led to groundbreaking findings on the brain basis of various aspects of behavior and has raised interest in possible clinical and practical applications of these methods. On the other hand, it has also triggered increasingly critical debates about the properties and possible limitations of these methods. In this review, we discuss these issues, clarify the challenges associated with the use of currently available NIBS techniques for basic research and practical applications, and provide recommendations for studies using NIBS techniques to establish brain-behavior relationships.

Indexed as

AnimalsBehaviorBrainHumansTranscranial Direct Current StimulationTranscranial Magnetic Stimulation

Identifiers

PMID29311747

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.