ArticleNature neuroscience2018
Social transmission and buffering of synaptic changes after stress.
Article in Nature neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
103 citing papers in PubMed, 190 citations in OpenAlex.
- Targeting dopamine transporter for treating social transmission of depression-like behaviors in male mice.Nature communications · 2026Article
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- State-dependent reward circuit modulation gates social buffering of stress.Research square · 2026Article
- Homeostatic scaling ensures behavioural stability during corticosterone negative feedback.Molecular psychiatry · 2026Article
- Experience-dependent modulation of prosocial touch in mice.iScience · 2026Article
- Neural Mechanisms of Social Homeostasis: Dynamic Range Plasticity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Review
- The Anterior Cingulate Cortex and Prosocial Behavior toward Others in Negative State.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Review
- If you give a mouse a poopsicle: a novel fecal microbiota transplant method for exploring the role of the gut microbiome in stress-related outcomes in mice.bioRxiv : the preprint server for biology · 2026Article
- CRH neurons in the AM-ACC circuit drive chronic pain and anxiety comorbidity.Frontiers in neuroscience · 2026Article
- If you give a mouse a poopsicle: a novel fecal microbiota transplant method for exploring the role of the gut microbiome in stress-related outcomes in mice.Frontiers in immunology · 2026Article
- Acute Stress Attenuates Hepatic Ischemia-Reperfusion Injury via Hypothalamic CRH Neuron-Induced HPA Axis Activation.CNS neuroscience & therapeutics · 2026Article
- Pairing Mouse Social and Aversive Stimuli across Sexes Does Not Produce Social Aversion in Females.eNeuro · 2025Article
- Sex Differences in Pain Contagion Determined by the Balance of Oxytocin and Corticosterone in the Anterior Cingulate Cortex in Rodents.Neuroscience bulletin · 2025Article
- Stranger-directed consolation-like behavior in mice in a test of social decision making.Hormones and behavior · 2025Article
- Oxytocin signaling regulates maternally directed behavior during early life.Science (New York, N.Y.) · 2025Article
- Hyperpolarization-Activated Channel 1 Modulates Resilience and Susceptibility to Social Avoidance Induced by Witnessing Social Defeat Stress.Biological psychiatry · 2025Article
- Paternal predatory risk alters parental behavior and offspring phenotypes in biparental Brandt's voles.Current zoology · 2025Article
- Brain circuits that regulate social behavior.Molecular psychiatry · 2025Review
- Fear Synchrony of Mouse Dyads: Interaction of Sex Composition and Stress.Biological psychiatry global open science · 2025Article
- Stress transmission in social groups of mice: unveiling physiological responses, behavioral patterns, and immune dynamics.iScience · 2025Article
43 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stress can trigger enduring changes in neural circuits and synapses. The behavioral and hormonal consequences of stress can also be transmitted to others, but whether this transmitted stress has similar effects on synapses is not known. We found that authentic stress and transmitted stress in mice primed paraventricular nucleus of the hypothalamus (PVN) corticotropin-releasing hormone (CRH) neurons, enabling the induction of metaplasticity at glutamate synapses. In female mice that were subjected to authentic stress, this metaplasticity was diminished following interactions with a naive partner. Transmission from the stressed subject to the naive partner required the activation of PVN CRH neurons in both subject and partner to drive and detect the release of a putative alarm pheromone from the stressed mouse. Finally, metaplasticity could be transmitted sequentially from the stressed subject to multiple partners. Our findings demonstrate that transmitted stress has the same lasting effects on glutamate synapses as authentic stress and reveal an unexpected role for PVN CRH neurons in transmitting distress signals among individuals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.