ArticleScientific reports2018
Anti-glioma Natural Products Downregulating Tumor Glycolytic Enzymes from Marine Actinomycete Streptomyces sp. ZZ406.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 46 citations in OpenAlex.
- Prospects of marine-derived compounds as potential therapeutic agents for glioma.Pharmaceutical biology · 2024Review
- Investigational Microbiological Therapy for Glioma.Cancers · 2022Review
- New Hygrocins K-U and Streptophenylpropanamide A and Bioactive Compounds from the Marine-AssociatedAntibiotics (Basel, Switzerland) · 2022Article
- Antiglioma Natural Products from the Marine-Associated FungusMolecules (Basel, Switzerland) · 2022Article
- Cytotoxic compounds from marine actinomycetes: Sources, Structures and Bioactivity.Acta materia medica · 2022Article
- Natural Products from Actinomycetes Associated with Marine Organisms.Marine drugs · 2021Review
- Therapeutic applications and biological activities of bacterial bioactive extracts.Archives of microbiology · 2021Review
- New Antiproliferative Compounds against Glioma Cells from the Marine-Sourced FungusMarine drugs · 2021Article
- Bioactive Compounds with Antiglioma Activity from Marine Species.Biomedicines · 2021Review
- The Genome Analysis of the Human Lung-AssociatedMicroorganisms · 2021Article
- Small Molecules of Marine Origin as Potential Anti-Glioma Agents.Molecules (Basel, Switzerland) · 2021Review
- New Antifungal Metabolites from the Mariana Trench Sediment-Associated ActinomyceteMarine drugs · 2020Article
- Bioactive Metabolites from the Mariana Trench Sediment-Derived FungusMarine drugs · 2020Article
- Novel Antimicrobial Indolepyrazines A and B from the Marine-AssociatedMarine drugs · 2019Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Marine natural products are important resources for discovering novel anticancer drugs. In this study, an extract prepared from the culture of a sea anemone-derived actinomycete Streptomyces sp. ZZ406 in soluble starch and casein-related liquid medium was found to have activity in inhibiting the proliferation of glioma cells and reducing the production of lactate in glioma cells. Chemical investigation of this active crude extract resulted in the isolation of four new compounds and seven known ones. Structures of the new compounds were determined by a combination of extensive NMR analyses, HRESIMS and MS-MS data, electronic circular dichroism calculation, chemical degradation, and Marfey's method. New compound 1 showed potent activity against the proliferation of different glioma cells with IC
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