Evidence map›Paper›PMID 29311654›Full record

ArticleScientific reports2018

Bidirectional modulation between infiltrating CD3

Ya-Lan Zhou, Shu-Zhuan Zhou, Hao-Ling Li, Man-Li Hu, Hui Li, Qing-Huan Guo, Xiao-Ming Deng, Yu-Qiu Zhang, Hua Xu

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Glial cells in neuropathic pain.Physiological reviews · 2026
    Review
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  3. Article
  4. Review
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  9. Intrathecal Administration of an Anti-nociceptive Non-CpG Oligodeoxynucleotide Reduces Glial Activation and Central Sensitization.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2021
    Article
  10. Review
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  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Ya-Lan ZhouDepartment of Anesthesiology, Changhai Hospital, The Second Military Medical University, Shanghai, 200433, China.
Shu-Zhuan ZhouDepartment of Anesthesiology, Changhai Hospital, The Second Military Medical University, Shanghai, 200433, China.
Hao-Ling LiDepartment of Anesthesiology, Changhai Hospital, The Second Military Medical University, Shanghai, 200433, China.
Man-Li HuInstitutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, 200032, China.
Hui LiInstitutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, 200032, China.
Qing-Huan GuoInstitutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, 200032, China.
Xiao-Ming DengDepartment of Anesthesiology, Changhai Hospital, The Second Military Medical University, Shanghai, 200433, China.
Yu-Qiu ZhangInstitutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, 200032, China. yuqiuzhang@fudan.edu.cn.
Hua XuDepartment of Anesthesiology, Changhai Hospital, The Second Military Medical University, Shanghai, 200433, China. pshhuaxu@163.com.
Changhai Hospital · CNFudan University · CNState Key Laboratory of Medical NeurobiologySecond Military Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increasing evidence suggests that T cells and glia participate in the process of neuropathic pain. However, little is known about the involvement of T cells or the interaction between glia and T cells at the molecular level. Here we investigated the phenotype of T cell infiltration into the spinal cord in inflammatory pain and explored potential crosstalk between glia and T cells. The establishment of monoarthritis produced T cell infiltration and astrocyte activation, exhibiting similar kinetics in the spinal cord. T-cell-deficient (Rag1

Indexed as

AnimalsArthritisAstrocytesDisease Models, AnimalGlial Fibrillary Acidic ProteinHomeodomain ProteinsHyperalgesiaInterferon-gammaLymphocyte ActivationNeurogliaNF-kappa BPhosphorylationRatsSpinal CordSpinal Cord Dorsal HornT-LymphocytesGlial Fibrillary Acidic ProteinHomeodomain ProteinsInterferon-gammaNF-kappa BRAG-1 protein

Identifiers

PMID29311654
PMCPMC5758647
OpenAlexW2781921829

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.