Evidence map›Paper›PMID 29311572›Full record

ArticleScientific reports2018

Correlative Factors of the Deterioration of Necrotizing Enterocolitis in Small for Gestational Age Newborns.

Lijuan Luo, Wenbin Dong, Lingping Zhang, Xuesong Zhai, Qingping Li, Xiaoping Lei

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lijuan LuoDepartment of Newborn Medicine, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.
Wenbin DongDepartment of Newborn Medicine, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.
Lingping ZhangDepartment of Newborn Medicine, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.
Xuesong ZhaiDepartment of Newborn Medicine, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.
Qingping LiDepartment of Newborn Medicine, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.
Xiaoping LeiDepartment of Newborn Medicine, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China. leixiaopingdeyx@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Small for gestational age (SGA) infants have an increased risk of necrotizing enterocolitis (NEC), but SGA has been found to not be a risk factor for the deterioration of NEC in previous literature. Few studies have focused on correlative factors of the progression of NEC in SGA newborns. The present retrospective observational study was performed in 64 SGA infants with Bell's stage II NEC. The dependent variable was Bell's stage II NEC that progressed to stage III after diagnosis. A stepwise forward multivariate logistic regression model was used to select potential correlative factors for the progression of NEC in SGA newborns. The results showed that elevation of CRP after NEC diagnosis (aOR 39.21, 95% CI 6.62-249.2) has an increased risk for deteriorating Bell's stage II NEC. In contrast, NEC in infants with congenital heart disease had a decreased risk of deterioration (aOR 0.11, 95% CI 0.01-0.92). Our findings indicated that serial CRP measurements post NEC diagnosis may be useful in predicting the deterioration of NEC.

Indexed as

Infant, Small for Gestational AgeDisease ProgressionEnterocolitis, NecrotizingHumansIncidenceInfantInfant, NewbornInfant, Premature, DiseasesOdds RatioRisk FactorsSeverity of Illness Index

Identifiers

PMID29311572
PMCPMC5758570

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.