Evidence map›Paper›PMID 29311570›Full record

SynthesisScientific reports2018

A Systematic Review and Meta-analysis of the Topical Administration of Fibrin Sealant in Total Hip Arthroplasty.

Zhihu Zhao, Xinlong Ma, Jianxiong Ma, Xiaolei Sun, Fengbo Li, Jianwei Lv

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06405659 (Immediate Fever During Anaesthesia Recovery After Surgical Procedure With Scoliosis), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06405659 completednot on this map

Immediate Fever During Anaesthesia Recovery After Surgical Procedure With Scoliosis: A Case Report and Literature Review

TypeobservationalSponsorAffiliated Hospital of Guangdong Medical UniversityRan2018 to 2023Enrolled1ConditionsFever, Scoliosis, Surgical Trauma, HypothermiaArmscorrection for pedicle fixation
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Zhihu ZhaoOrthopaedics Institute, Tianjin Hospital, Tianjin, 300050, People's Republic of China.
Xinlong MaOrthopaedics Institute, Tianjin Hospital, Tianjin, 300050, People's Republic of China. gukezzh@126.com.
Jianxiong MaBiomechanics Labs of Orthopaedics Institute, Tianjin Hospital, Tianjin, 300050, People's Republic of China.
Xiaolei SunOrthopaedics Institute, Tianjin Hospital, Tianjin, 300050, People's Republic of China.
Fengbo LiOrthopaedics Institute, Tianjin Hospital, Tianjin, 300050, People's Republic of China.
Jianwei LvOrthopaedics Institute, Tianjin Hospital, Tianjin, 300050, People's Republic of China.
Tianjin Hospital · CNTianjin People's Hospital · CNTianjin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients who undergo total hip arthroplasty (THA) may experience a large amount of blood loss. The objective of our study is to include randomized controlled trials (RCTs) and compare the clinical outcomes of fibrin sealant (FS) versus placebo after a THA. In October 2015, we searched the following databases: Medline, Embase, PubMed, the Cochrane Controlled Trials Register, Web of Science, the China National Knowledge Infrastructure, the China Wanfang database and Google Scholar. Finally, seven studies that included 679 patients met the inclusion criteria. The meta-analysis indicated that the topical administration of FS was associated with a reduction of the need for transfusion compared to the control group (P = 0.05). And topical FS will reduce total blood loss after THA (P = 0.0003) and blood loss in drainage (P = 0.002). However, there was no significant difference in terms of the intraoperative blood loss (P = 0.62) and the rate of deep venous thrombosis (DVT), fever, pain, anemia, hematoma and oozing. In conclusion, the use of FS in patients who are undergoing THA may reduce perioperative blood loss and attenuate the decrease in Hb. Furthermore, FS do not decrease the intraoperative blood loss without an increase in the risk of postoperative DVT, fever, pain, anemia, hematoma and oozing.

Indexed as

Arthroplasty, Replacement, HipAdministration, TopicalBlood Loss, SurgicalBlood TransfusionFibrin Tissue AdhesiveHumansOdds RatioTreatment OutcomeFibrin Tissue Adhesive

Identifiers

PMID29311570
PMCPMC5758515
OpenAlexW2782208222

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.