Evidence map›Paper›PMID 29311525›Full record

ArticleThe Journal of reproduction and development2018

Evaluating the electrical impedance and mucus-related gene expression of uterine endometrial tissues in mares.

Kohta Kikuchi, Keisuke Kozai, Takuo Hojo, Miki Sakatani, Kiyoshi Okuda, Hanako Bai, Manabu Kawahara, Masashi Takahashi

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of reproduction and development, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 100% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Kohta KikuchiLaboratory of Animal Genetics and Reproduction, Department of Animal Science, Research Faculty of Agriculture, Hokkaido University, Hokkaido 060-8589, Japan.
Keisuke KozaiLaboratory of Animal Reproductive Physiology, Graduate School of Environmental and Life Science, Okayama University, Okayama 700-8530, Japan.
Takuo HojoLivestock and Grassland Research Division, Kyushu Okinawa Agricultural Research Center, NARO, Kumamoto 861-1192, Japan.
Miki SakataniLivestock and Grassland Research Division, Kyushu Okinawa Agricultural Research Center, NARO, Kumamoto 861-1192, Japan.
Kiyoshi OkudaLaboratory of Animal Reproductive Physiology, Graduate School of Environmental and Life Science, Okayama University, Okayama 700-8530, Japan.
Hanako BaiLaboratory of Animal Genetics and Reproduction, Department of Animal Science, Research Faculty of Agriculture, Hokkaido University, Hokkaido 060-8589, Japan.
Manabu KawaharaLaboratory of Animal Genetics and Reproduction, Department of Animal Science, Research Faculty of Agriculture, Hokkaido University, Hokkaido 060-8589, Japan.
Masashi TakahashiLaboratory of Animal Genetics and Reproduction, Department of Animal Science, Research Faculty of Agriculture, Hokkaido University, Hokkaido 060-8589, Japan.
Hokkaido University · JPKyushu Okinawa Agricultural Research Center · JPInstitute for Reproductive Health · USObihiro University of Agriculture and Veterinary Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the electrical impedance of the reproductive tracts (vagina and uterine endometrial tissues) and the expression of mucus-related genes to identify the stage of the estrous cycle in mares. We first examined vaginal impedance in native Hokkaido mares during their estrous cycle and found no significant differences. However, impedance levels tended to decrease towards ovulation. Furthermore, we investigated the estrous cycle by measuring the electrical impedance of the uterine endometrial tissues obtained from carcasses of mares. We found that impedance levels in the endometrial tissues decreased in the regressed phase of the corpus luteum (CL). Expression of mucus-related genes (ATP1A1, CFTR, AQP3, and AQP5) varied at different stages of the estrous cycle. Among them, AQP3 expression was consistent with previous reports. We concluded that electrical impedance in the uterine endometrial tissues of mares could be potentially used to verify the presence of active CL in horses for experimental purposes. However, further studies are needed to determine the reference value and to identify the day of the estrous cycle in mares.

Indexed as

Estrus DetectionGene Expression Regulation, DevelopmentalAbattoirsAnimalsAnimals, Inbred StrainsAquaporin 3Aquaporin 5Cystic Fibrosis Transmembrane Conductance RegulatorElectric ImpedanceEndometriumFeasibility StudiesFemaleHorsesJapanLuteinizationLuteolysisAquaporin 3Aquaporin 5Cystic Fibrosis Transmembrane Conductance RegulatorSodium-Potassium-Exchanging ATPaseElectrical impedanceEquineEstrous cycleMucus-related gene

Identifiers

PMID29311525
PMCPMC5902908
OpenAlexW2782143544

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.