Evidence map›Paper›PMID 29311363›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

IL-1 Signaling Prevents Alveolar Macrophage Depletion during Influenza and

Shruti Bansal, Vijaya Kumar Yajjala, Christopher Bauer, Keer Sun

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. RSV enhancesInfection and immunity · 2024
    Article
  6. Article
  7. IL-10 Counteracts IFN-γ to Alleviate Acute Lung Injury in a Viral-Bacterial Superinfection Model.American journal of respiratory cell and molecular biology · 2024
    Article
  8. Article
  9. Innate immune responses in pneumonia.Pneumonia (Nathan Qld.) · 2023
    Review
  10. Neuronal Serpina3n is an endogenous protector against blood brain barrier damage following cerebral ischemic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. In and out:Frontiers in cellular and infection microbiology · 2022
    Article
  18. Antibiotics as immunomodulators: a potential pharmacologic approach for ARDS treatment.European respiratory review : an official journal of the European Respiratory Society · 2021
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Shruti BansalDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198-5900.
Vijaya Kumar YajjalaDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198-5900.
Christopher BauerDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198-5900.ORCID 0000-0002-5652-9582
Keer SunDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198-5900 Keer.sun@unmc.edu.ORCID 0000-0002-9702-9584
University of Nebraska Medical Center · US

Funding

Oxidative Burst in Influenza and MRSA Co-infectionR01HL118408 · NHLBI · UNIVERSITY OF TEXAS MED BR GALVESTON · PI SUN, KEER · 2013 to 2022
$3.9M
NHLBI NIH HHS R01 HL118408
6 · The paper itself

Abstract

Influenza and bacterial coinfection is a significant cause of hospitalization and death in humans during influenza epidemics and pandemics. However, the fundamental protective and pathogenic mechanisms involved in this complex virus-host-bacterium interaction remain incompletely understood. In this study, we have developed mild to lethal influenza and

Indexed as

AnimalsCoinfectionHumansInfluenza A Virus, H3N2 SubtypeInterleukin-1Macrophages, AlveolarMiceMice, Inbred C57BLMice, KnockoutOrthomyxoviridae InfectionsPneumococcal InfectionsSignal TransductionInterleukin-1

Identifiers

PMID29311363
PMCPMC5809299
OpenAlexW2783326957

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.