ArticleJournal of immunology (Baltimore, Md. : 1950)2018
Multiple Levels of Control Determine How E4bp4/Nfil3 Regulates NK Cell Development.
Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 31 citations in OpenAlex.
- E4BP4 safeguards brown fat mitochondria from obesity-induced fragmentation via ceramide repression.EMBO reports · 2026Article
- Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure.Cell proliferation · 2025Review
- Circadian rhythms in solid organ transplantation.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2024Review
- Circadian immunity from bench to bedside: a practical guide.The Journal of clinical investigation · 2024Review
- Modern broiler chickens exhibit a differential gastrointestinal immune and metabolic response to repeated CpG injection relative to a 1950s heritage broiler breed.Frontiers in physiology · 2024Article
- Review
- NFIL3 deficiency alleviates EAE through regulating different immune cell subsets.Journal of advanced research · 2022Article
- Fra-2 Is a Dominant Negative Regulator of Natural Killer Cell Development.Frontiers in immunology · 2022Article
- NFIL3 and its immunoregulatory role in rheumatoid arthritis patients.Frontiers in immunology · 2022Article
- NKL-Code in Normal and Aberrant Hematopoiesis.Cancers · 2021Review
- Pathogenetic profiling of COVID-19 and SARS-like viruses.Briefings in bioinformatics · 2021Article
- SUMO and SUMOylation Pathway at the Forefront of Host Immune Response.Frontiers in cell and developmental biology · 2021Review
- Hepatic E4BP4 induction promotes lipid accumulation by suppressing AMPK signaling in response to chemical or diet-induced ER stress.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020Article
- E4BP4-mediated inhibition of T follicular helper cell differentiation is compromised in autoimmune diseases.The Journal of clinical investigation · 2020Article
- Circadian Rhythms in Immunity.Current allergy and asthma reports · 2020Review
- Molecular Regulation of NK Cell Maturation.Frontiers in immunology · 2020Review
- Shared Transcriptional Control of Innate Lymphoid Cell and Dendritic Cell Development.Annual review of cell and developmental biology · 2019Review
- Transcriptional control of natural killer cell differentiation.Immunology · 2019Review
- An Essential Role of Innate Lymphoid Cells in the Pathophysiology of Graft-vs.-Host Disease.Frontiers in immunology · 2019Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
The transcription factor E4bp4/Nfil3 has been shown to have a critical role in the development of all innate lymphoid cell types including NK cells. In this study, we show that posttranslational modifications of E4bp4 by either SUMOylation or phosphorylation have profound effects on both E4bp4 function and NK cell development. We examined the activity of E4bp4 mutants lacking posttranslational modifications and found that
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.